Abstract: Active enamel substances may be used for the preparation of a pharmaceutical or cosmetic composition for healing of a wound, improving healing of a wound, soft tissue regeneration or repair, or for preventing or treating infection or inflammation.
Type:
Grant
Filed:
October 30, 2003
Date of Patent:
November 13, 2007
Assignee:
Biora BioEx AB
Inventors:
Stina Gestrelius, Lars Hammarström, Petter Lyngstadaas, Christer Andersson, Ivan Slaby, Tomas Hammargren
Abstract: The present invention relates to the use of enamel matrix, enamel matrix derivatives and/or enamel matrix proteins as therapeutic and/or cosmetic agents. These substances are used for the manufacture of a pharmaceutical and/or cosmetic composition for actively inducing, guiding and/or stimulating connective tissue growth and thus to prevent connective tissue scarring and/or contraction in a wound cavity and/or tissue defect that is characterized by a substantial loss of tissue. The invention comprises, in particular, the use of active enamel substances for guided connective soft tissue growth and resistance to contraction in deep cavity shaped wounds following loss or removal of significant volumes of tissue, such as e.g., after surgical removal of a tumor and especially in combination with radiation therapy.
Abstract: Enamel matrix, enamel matrix derivatives and/or enamel matrix proteins are used in the preparation of a pharmaceutical composition for promoting the take of a graft, e.g. in soft tissue such as skin or mucosa or mineralized tissue such as bone.
Abstract: Active enamel substances may be used for the preparation of a pharmaceutical or cosmetic composition for healing of a wound, improving healing of a wound, soft tissue regeneration or repair, or for preventing or treating infection or inflammation.
Type:
Grant
Filed:
May 28, 2002
Date of Patent:
April 13, 2004
Assignee:
Biora BioEx AB
Inventors:
Stina Gestrelius, Lars Hammarström, Petter Lyngstadaas, Christer Andersson, Ivan Slaby, Tomas Hammargren
Abstract: Active enamel substances may be used for the preparation of a pharmaceutical or cosmetic composition for healing of a wound, improving healing of a wound, soft tissue regeneration or repair, or for preventing or treating infection or inflammation.
Type:
Application
Filed:
May 28, 2002
Publication date:
April 3, 2003
Applicant:
Biora BioEx AB
Inventors:
Stina Gestrelius, Lars Hammarstrom, Petter Lyngstadaas, Christer Andersson, Ivan Slaby, Tomas Hammargren
Abstract: Active enamel substances may be used for the preparation of a pharmaceutical or cosmetic composition for healing of a wound, improving healing of a wound, soft tissue regeneration or repair, or for preventing or treating infection or inflammation.
Type:
Grant
Filed:
February 26, 1999
Date of Patent:
January 7, 2003
Assignee:
Biora BioEx AB
Inventors:
Stina Gestrelius, Lars Hammarström, Petter Lyngstadaas, Christer Andersson, Ivan Slaby, Tomas Hammargren