Patents Assigned to Biosearch
  • Benzazolides and their employment in phosphite ester oligonucleotide synthesis processes
    Patent number: 4474948
    Abstract: Benzotriazoles are employed in phosphite triester oligonucleotide synthesis. The benzotriazoles also form phosphinedibenzazolides. Processes employing these reagents are also disclosed.
    Type: Grant
    Filed: April 8, 1982
    Date of Patent: October 2, 1984
    Assignee: Biosearch
    Inventors: Derek Hudson, Ronald M. Cook
  • Benzazolides and their employment in phosphate ester oligonucleotide synthesis processes
    Patent number: 4474947
    Abstract: Benzazoles, including benzatriazoles and benzimidazoles are employed in phospate triester oligonucleotide synthesis. The benzazoles form arylbenzazolide coupling agents, and phosphorodibenzazolides. Processes employing these reagents are also disclosed.
    Type: Grant
    Filed: April 8, 1982
    Date of Patent: October 2, 1984
    Assignee: Biosearch
    Inventors: Derek Hudson, Ronald M. Cook