Abstract: The invention relates to a strain of the Lactobacillus salivarius species deposited in the Spanish Type Culture Collection (CECT) with accession number 5713 or a mutant thereof for use in the treatment and/or prevention of infertility or recurrent pregnancy loss in a female subject. Additionally, the invention relates to an in vitro monitoring method for monitoring the effect of a treatment for infertility or recurrent pregnancy loss in a female subject with a strain of the Lactobacillus salivarius species deposited in the CECT with accession number 5713 or a mutant thereof.
Type:
Application
Filed:
June 10, 2020
Publication date:
July 6, 2023
Applicant:
Biosearch, S.A.
Inventors:
Leónides FERNÁNDEZ ÁLVAREZ, Irma CASTRO NAVARRO, Rebeca ARROYO RODRÍGUEZ, Claudio ALBA RUBIO, Juan Miguel RODRÍGUEZ GÓMEZ
Abstract: The invention relates to biological biocomposites which comprise a collagen scaffold containing probiotics entrapped into the collagen scaffold and exopolysaccharides. The invention also relates to methods for obtaining the biocomposites as well as to the use of biocomposites in medicine and, more in particular, in the treatment of bacterial vaginosis.
Type:
Application
Filed:
March 15, 2021
Publication date:
May 4, 2023
Applicant:
Biosearch, S.A.
Inventors:
Mónica OLIVARES MARTÍN, Óscar BAÑUELOS HORTIGÜELA, José Manuel DOMÍNGUEZ VERA, Ana GONZÁLEZ GARNICA, José Manuel DELGADO LÓPEZ, Laura SABIO RODRÍGUEZ, Gloria Belén RAMÍREZ RODRÍGUEZ
Abstract: The invention relates to a probiotic strain selected from Lactobacillus reuteri V340 with accession number CECT and Bifidobacterium breve BT820 with accession number CECT 8606, or a variant of said probiotic strain having cholesterol-absorbing capacity, and to methods and therapeutic uses thereof. The invention also relates to compositions, pharmaceutical compositions, feeds or nutritional products comprising a probiotic strain selected from Lactobacillus reuteri V3401 with accession number CECT 8605 and Bifidobacterium breve BT820 with accession number CECT 8606, or a variant of said probiotic strain having cholesterol-absorbing capacity.
Type:
Grant
Filed:
December 10, 2015
Date of Patent:
July 13, 2021
Assignee:
BIOSEARCH, S.A.
Inventors:
Ana Isabel Sañudo Otero, Raquel Criado García, Alba Rodríguez Nogales, Alberto Garach Domech, Mónica Olivares Martín, Julio Juan Gálvez Peralta, Santiago De La Escalera Huerso, Juan Manuel Duarte Pérez, Antonio Zarzuelo Zurita, Óscar Bañuelos Hortigüela
Abstract: The invention relates to probiotic bacteria selected from lactic acid bacteria, such as Lactobacillus and Bifidobacteria, having metals and/or metal nanoparticles and to foodstuff and pharmaceutical composition having these bacteria. The invention also provides methods for obtaining these bacteria and uses of these bacteria for the treatment and prevention of mineral deficiency pathologies, as a contrast agent for the imaging of the digestive tract and for the treatment of cancer.
Type:
Grant
Filed:
June 24, 2014
Date of Patent:
April 30, 2019
Assignee:
BIOSEARCH, S.A.
Inventors:
Jose Manuel Dominguez Vera, Natividad Galvez Rodriguez, Miguel Angel Martin Marcos, Fernando Carmona Rodriguez-Acosta, Deyanira Rondon Rodriguez, Monica Olivares Martin
Abstract: The present disclosure concerns phenolic extracts containing procyanidins, propelargonidins and prodelfinidins obtained from peel of the almond [Prunus dulcís (Mili.) D. A. Webb, Prunus amygdalus (L.) Batsch., Amygdalus dulcís (Mili.), Amygdalus communis (L.) or Prunus communis (L.)]. In particular, the objective is to obtain extracts rich in proanthocyanidins with type-A bonds. The preparation method disclosed comprises: (a) a maceration of plant material with organic solvents at 25-100° C., (b) purification by liquid-liquid extraction and/or adsorption or ion exchange chromatography, and (c) optionally, a final drying. Also disclosed are the possible activities/properties of these extracts such as anti-oxidant activity and others, which determine the use thereof as a nutritional or health ingredient, and the use thereof in the cosmetic and pharmaceutical industry.
Type:
Grant
Filed:
May 28, 2008
Date of Patent:
August 12, 2014
Assignees:
Consejo Superior de Investigaciones Cientificas, Biosearch, S.A.
Inventors:
Begoña Bartolomé´Sualdea, María Monagas Juan, Ignacio Garrido Lafuente, María Carmen Gómez-Cordovés De La Vega, Rosa Lebrón Aguilar, José Carlos Quintela Fernandez, Esther De La Fuente García, Alejandro Jara García-Navas