Patents Assigned to Biosensor Laboratories Co., Ltd.
  • Patent number: 5981202
    Abstract: A method for assaying a substance is provided in which an optical image is obtained from spots of light emitted from a chemiluminescent material capable of undergoing a luminescent reaction. The method comprises: (a) a step of distributing solid particles on the surface of a support, the solid particles having a diameter of not more than 100 .mu.
    Type: Grant
    Filed: March 3, 1995
    Date of Patent: November 9, 1999
    Assignee: Biosensor Laboratories Co., Ltd.
    Inventor: Masayuki Masuko
  • Patent number: 5674696
    Abstract: There is disclosed an apparatus for the determination of a trace amount of an analyte substance or organism. A substrate solution is brought into contact with a small diameter tube which has captured, at least on its inner surface, a trace amount of an analyte substance or organism. The trace amount has the ability to change the pH of the substrate solution.
    Type: Grant
    Filed: October 24, 1994
    Date of Patent: October 7, 1997
    Assignee: Biosensor Laboratories Co., Ltd.
    Inventors: Michihiro Nakamura, Satomi Matsui, Keiko Oka, Hitoshi Tsuruta
  • Patent number: 5637874
    Abstract: The present invention provides a chemiluminescence measuring apparatus which is small in size and high in operability and has a function of performing accurate quantitative analysis and the like. The apparatus includes at least a box-like housing having an opening, a cover provided on a top surface of the housing and having a through hole for introducing a first detachable vessel into the inner space of the housing, a holder having a concave portion and enclosing the opening of the housing, the hollow chamber having an opening at a side wall thereof and partially housing a second vessel, a photo-sensing unit for detecting luminescence from the second vessel via the through hole of the hollow chamber, and a shutter mechanism for intermittently cutting optical path between the photo-sensing unit and the second vessel.
    Type: Grant
    Filed: February 23, 1995
    Date of Patent: June 10, 1997
    Assignee: Biosensor Laboratories Co., Ltd.
    Inventors: Katsu Honzawa, Kazuhiro Atsumi, Fumihiko Shimomura, Masayuki Masuko, Tsuyoshi Hayakawa
  • Patent number: 5576212
    Abstract: An oxidizing composition in the form of powder for oxidizing a chemiluminescent substance, including an oxidizing agent and a binder.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: November 19, 1996
    Assignee: Biosensor Laboratories Co., Ltd.
    Inventors: Katsu Honzawa, Seiji Kawaguchi, Kazuhiro Atsumi, Fumihiko Shimomura, Takahiko Ishiguro, Hisaya Motojima
  • Patent number: 5523845
    Abstract: The first branch 1a of the optical fiber 1 is connected to the light source 2, and the second branch 1b is connected to the optical measuring unit 3. A taper-shaped tip member 8 is fitted to a tip end of the optical fiber unit 1 with the use of a jig member 4. The inner hollow space 7 in the tip member 8 is connected with the air suction device 11, through the gap 5 formed between the optical fiber unit 1 and the jig member 4 and the air suction tube 10. The air suction device 11 discharges air from the inner hollow space 7 to suck liquid through the through-hole 6 into the inner hollow space. The air suction device 11 is controlled by the controller 12. Because the optical fiber unit can directly irradiate liquid with light, measurement can be performed with high sensitivity. The optical fiber unit is prevented from contamination.
    Type: Grant
    Filed: January 25, 1995
    Date of Patent: June 4, 1996
    Assignee: Biosensor Laboratories Co., Ltd.
    Inventors: Katsu Honzawa, Kazuhiro Atsumi, Humihiko Shimomura, Seiji Kawaguchi, Yuichiro Sakamoto, Hisaya Motojima, Masayuki Masuko, Tsuyoshi Hayakawa
  • Patent number: 5324835
    Abstract: Compounds useful as luminescent labelling reagents or reagents for determining hydrogen peroxide of the following formula: ##STR1## Wherein R is selected from the group consisting of hydrogen, amino, carboxyl, thiol, n-propyl, isopropyl, n-butyl, sec-butyl, benzyl, carboxyethyl, tert-butyl, and--(CH.sub.2).sub.n1 CH.sub.3 wherein n.sub. is 0 or an integer of 1-15;--(CH.sub.2).sub.n2 COOH wherein n.sub.2 is 0 or an integer of 1-5;--CH.sub.2 SH; --CH.sub.2 X.sub.1 wherein X is Br, Cl or F;--(CH.sub.2).sub.n3 NH.sub.2 wherein n.sub.3 is an integer of 1-5; ##STR2## wherein n.sub.4 is 0 or 1 and n.sub.5 is 0 or ##STR3## wherein n.sub.6 is 0 or 1 and X.sub.2 is H, Br, Cl, F or I; and --(CH.sub.2).sub.n7 R.sub.1 wherein n.sub.7 is 0 or an integer of 1-5 and R.sub.1 is selected from COCl, CON.sub.3, CONHNH.sub.
    Type: Grant
    Filed: August 7, 1992
    Date of Patent: June 28, 1994
    Assignee: Biosensor Laboratories Co., Ltd.
    Inventor: Masatoshi Yamaguchi