Abstract: Disclosed herein are system, method, and computer-readable medium aspects for removing and detecting pacing artifacts from electrocardiogram and cardiac electrogram signals. An aspect includes a circuit board. The circuit board comprises two signal paths configured to receive a signal comprising cardiac data, pacing data, and background electrical noise. The first path comprises a first filter configured to amplify the cardiac data of the signal and suppress the pacing data of the signal. The second path comprises a second filter configured to amplify the pacing data of the signal and suppress the cardiac data of the signal. The circuit board also comprises a thresholding generator configured to establish a threshold amplitude value. The circuit board further comprises a thresholding module configured to apply the threshold amplitude value to the signal, thereby removing parts of amplitude of the signal that are less than or equal to the threshold amplitude value.

Abstract: Disclosed herein are system and method aspects for monitoring changes in a negative component of a unipolar electrogram. The system can include a memory and at least one processor coupled to the memory. The at least one processor can be configured to receive a unipolar electrogram signal from a catheter, display on at least one digital display a signal waveform based on the unipolar electrogram signal using a first attribute. The signal waveform can represent one or more cycles from a patient's heart. The at least one processor can also be configured to monitor the signal waveform to detect a change in a negative component of the unipolar electrogram signal and to signal the change on the at least one digital display when the change is detected in at least a threshold number of consecutive cycles.

Abstract: Described herein are embodiments of a switching network for integrating electrophysiology components into an electrophysiology system. These electrophysiology components may include electrophysiology recorder, three-dimensional mapping systems, radio frequency generators, and stimulators. The switching network provides switchable connections, which allow the electrophysiology system to be reconfigured to perform different electrophysiology procedures, such as heart signal recording and mapping, cardiac ablation, or cardiac pacing. A recorder may provide control signals to the switching network to change connections between electrophysiology equipment and a catheter in a patient's heart. The electrophysiology system may control generation of biphasic pulses for use in cardiac pacing. The electrophysiology system may reconfigure the effective size the tip electrode of a split tip catheter.

Abstract: Systems, methods, and computer program product embodiments are disclosed for displaying cardiac signals based on a signal pattern. An embodiment operates by accessing an input cardiac signal. The embodiment matches a portion of the input cardiac signal to a known signal pattern. The embodiment then displays an indication of a degree of the match.

Abstract: Systems, methods, and computer program product embodiments are disclosed for removing any fixed frequency interfering signal from an input signal without introducing artifacts that are not part of the original signal of interest. An embodiment operates by using a virtual buffer with a length that matches a length of one cycle of an interfering signal. The embodiment extracts the interfering signal into the virtual buffer. For a sample in the next cycle of the interfering signal that corresponds to a virtual memory location for the virtual buffer, the embodiment can update one or more physical memory locations of the virtual buffer that are in the vicinity of the virtual memory location. This use of virtual buffer can remove any interfering signal without creating the artifacts associated with conventional notch filters.

Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.

Abstract: Methods, systems, and media are disclosed for reconstructing bioelectronic lead placement. In some embodiments, the disclosed system can include a processor configured to determine relationships between EP signals of one or more pairs of a plurality of electrodes over one or more sampling time periods, wherein the plurality electrodes are separately placed on a patient's body for collecting the EP signals, and to reconstruct geometry of the plurality of electrodes based on the relationships between the EP signals.

Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Abstract: Systems, methods, and computer program product embodiments are disclosed for removing any fixed frequency interfering signal from an input signal without introducing artifacts that are not part of the original signal of interest. An embodiment operates by using a virtual buffer with a length that matches a length of one cycle of an interfering signal. The embodiment extracts the interfering signal into the virtual buffer. For a sample in the next cycle of the interfering signal that corresponds to a virtual memory location for the virtual buffer, the embodiment can update one or more physical memory locations of the virtual buffer that are in the vicinity of the virtual memory location. This use of virtual buffer can remove any interfering signal without creating the artifacts associated with conventional notch filters.

Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Abstract: Systems, methods, and computer program product embodiments are disclosed for removing any fixed frequency interfering signal from an input signal without introducing artifacts that are not part of the original signal of interest. An embodiment operates by using a virtual buffer with a length that matches a length of one cycle of an interfering signal. The embodiment extracts the interfering signal into the virtual buffer. For a sample in the next cycle of the interfering signal that corresponds to a virtual memory location for the virtual buffer, the embodiment can update one or more physical memory locations of the virtual buffer that are in the vicinity of the virtual memory location. This use of virtual buffer can remove any interfering signal without creating the artifacts associated with conventional notch filters.

Abstract: Systems, methods, and computer program product embodiments are disclosed for removing any fixed frequency interfering signal from an input signal without introducing artifacts that are not part of the original signal of interest. An embodiment operates by using a virtual buffer with a length that matches a length of one cycle of an interfering signal. The embodiment extracts the interfering signal into the virtual buffer. For a sample in the next cycle of the interfering signal that corresponds to a virtual memory location for the virtual buffer, the embodiment can update one or more physical memory locations of the virtual buffer that are in the vicinity of the virtual memory location. This use of virtual buffer can remove any interfering signal without creating the artifacts associated with conventional notch filters.

Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.

Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Abstract: Systems, methods, and computer program product embodiments are disclosed for performing electrophysiology (EP) signal processing. An embodiment includes an electrocardiogram (ECG) circuit board configured to process an ECG signal. The embodiment further includes a plurality of intracardiac (IC) circuit boards, each configured to process a corresponding IC signal. The ECG circuit board and the plurality of IC circuit boards share substantially a same circuit configuration and components. The ECG circuit board further processes the ECG signal using substantially a same path as each IC circuit board uses to process its corresponding IC signal.

Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Abstract: Systems, methods, and computer program product embodiments are disclosed for removing any fixed frequency interfering signal from an input signal without introducing artifacts that are not part of the original signal of interest. An embodiment operates by using a virtual buffer with a length that matches a length of one cycle of an interfering signal. The embodiment extracts the interfering signal into the virtual buffer. For a sample in the next cycle of the interfering signal that corresponds to a virtual memory location for the virtual buffer, the embodiment can update one or more physical memory locations of the virtual buffer that are in the vicinity of the virtual memory location. This use of virtual buffer can remove any interfering signal without creating the artifacts associated with conventional notch filters.

Abstract: Apparatus and methods remove a voltage offset from an electrical signal, specifically a biomedical signal. A signal is received at a first operational amplifier and is amplified by a gain. An amplitude of the signal is monitored, by a first pair of diode stages coupled to an output of the first operational amplifier, for the voltage offset. The amplitude of the signal is then attenuated by the first pair of diode stages and a plurality of timing banks. The attenuating includes limiting charging, by the first pair of diode stages, of the plurality of timing banks and setting a time constant based on the charging. The attenuating removes the voltage offset persisting at a threshold for a duration of at least the time constant. Saturation of the signal is limited to a saturation recovery time while the saturated signal is gradually pulled into monitoring range over the saturation recovery time.

Abstract: Methods, systems, and media are disclosed for reconstructing bioelectronic lead placement. In some embodiments, the disclosed system can include a processor configured to determine relationships between EP signals of one or more pairs of a plurality of electrodes over one or more sampling time periods, wherein the plurality electrodes are separately placed on a patient's body for collecting the EP signals, and to reconstruct geometry of the plurality of electrodes based on the relationships between the EP signals.