Patents Assigned to Biosignal LTD
  • Electrode device
    Patent number: 11229390
    Abstract: Disclosed is an electrode device for measuring an electric biosignal. The electrode device includes a flexible PCB (printed circuit board) having a flexible support layer and a trace layer on a first side. The trace layer includes at least two electrode pads for skin contacts and, for each electrode pad, a solder pad and a conducting trace forming a galvanic connection between the electrode and the solder pad. The flexible PCB further includes an opening defining a flexible, elongated cantilever in a central portion of the flexible PCB, having a base end connected to the central portion and a free end separated from the central portion. The solder pads are located at the free end. The electrode device further includes a connector component on the second side, soldered to the solder pads on the free end of the cantilever.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: January 25, 2022
    Assignee: BITTIUM BIOSIGNALS LTD
    Inventor: Juha Matti Myllykangas
  • Treatment of platelet derived growth factor related disorders such as cancers
    Patent number: 6331555
    Abstract: The present invention concerns compounds which can inhibit platelet derived growth factor receptor (PDGF-R) activity, preferably such compounds also inhibit the activity other members of the PDGF-R super family and are selective for members of the PDGF-R super family. The PDGF-R super family includes PDGF-R and PDGF-R related kinases Flt, and KDR. The featured compounds are active on cell cultures to reduce the activity of the PDGF-R and preferably one or more PDGF-R related kinases. An example of a featured compound, A10 (see FIG. 1a), and its ability to inhibit growth of tumor cells in vivo is described below. Using the present application as guide other compounds able to inhibit PDGF-R and preferably Flt and/or KDR can be obtained. Such compounds are preferably used to treat patients suffering from cell proliferative disorders characterized by inappropriate PDGF-R activity.
    Type: Grant
    Filed: July 27, 1999
    Date of Patent: December 18, 2001
    Assignees: University of California, Yissum Research Development Company of the Hebrew University of Jerusalem, Biosignal LTD, Sugen, Inc., Max-Planck-Gesellschaft zur Forderung der Wissenschaften E.V.
    Inventors: Klaus P. Hirth, Elaina Mann, Laura K. Shawyer, Axel Ullrich, Istvan Szekely, Tamas Bajor, Janis Haimichael, Laszlo Orfi, Alex Levitzki, Aviv Gazit, Peng Cho Tang, Reiner Lammers
  • Treatment of platelet derived growth factor related disorders such as cancers
    Patent number: 5932602
    Abstract: The present invention concerns compounds which can inhibit platelet derived growth factor receptor (PDGF-R) activity, preferably such compounds also inhibit the activity other members of the PDGF-R super family and are selective for members of the PDGF-R super family. The PDGF-R super family includes PDGF-R and PDGF-R related kinases Flt, and KDR. The featured compounds are active on cell cultures to reduce the activity of the PDGF-R and preferably one or more PDGF-R related kinases. An example of a featured compound, A10 (see FIG. 1a), and its ability to inhibit growth of tumor cells in vivo is described below. Using the present application as guide other compounds able to inhibit PDGF-R and preferably Flt and/or KDR can be obtained. Such compounds are preferably used to treat patients suffering from cell proliferative disorders characterized by inappropriate PDGF-R activity.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: August 3, 1999
    Assignees: Sugen, Inc., Biosignal Ltd., The Regents of the University of California, Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V., Yissum Research and Development Company of the Hebrew University of Jerusalem
    Inventors: Klaus Peter Hirth, Laura Kay Shawver, Gyorgi Keri, Istvan Szekely, Janis Haimichael, Axel Ullrich, Reiner Lammers
  • Single site, multi-variable patient monitor
    Patent number: 5673692
    Abstract: An apparatus for monitoring multiple physiological variables of a patient at a single site on the patient can be used to facilitate assessment of the patient's well being during medical surgery as well as during ambulatory monitoring, home monitoring, procedure monitoring and similar situations. The apparatus has an infrared (IR) temperature sensor, a pulse oximeter sensor and a communication circuit for outputting information produced from the pulse oximeter and information produced from the infrared temperature measuring device. These elements are integrally placed within a mold or plug made to fit the ear of the patient.
    Type: Grant
    Filed: February 3, 1995
    Date of Patent: October 7, 1997
    Assignee: BioSignals Ltd. Co.
    Inventors: Arthur E. Schulze, Tommy G. Cooper