Patents Assigned to Biossil Inc.
  • Combination cancer therapy with pentaaza macrocyclic ring complex and platinum-based anticancer agent
    Patent number: 12773411
    Abstract: A method of treating a cancer in a mammalian subject afflicted with the cancer, consisting essentially of administering to the subject a therapeutically effective amount of a platinum-based anticancer agent, and administering to the subject a therapeutically effective amount of a pentaaza macrocyclic ring complex corresponding to the Formula (I) below, prior to, concomitantly with, or after administration of the platinum-based anticancer agent, whereby response of the cancer to the platinum-based anticancer agent is increased.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: October 27, 2026
    Assignees: Biossil Inc., Board of Regents of the University of Texas System
    Inventors: Jeffery L. Keene, Dennis P. Riley, Robert A. Beardsley, Michael Dean Story, Kranti Ashok Mapuskar, Douglas R. Spitz, Jr., Bryan G. Allen, Andrew Blake Davis, Diana Zepeda Orozco