Patents Assigned to Biostream, Inc.
  • Pendant fatty acid imaging agents
    Publication number: 20040081616
    Abstract: The disclosure provides pendant fatty acid compounds for use in diagnostic imaging, (particularly the cardiovascular system), as well as kits comprised of the same. The disclosure also provides for a method administering a imaging agent with a high specificity for the myocardium.
    Type: Application
    Filed: April 1, 2003
    Publication date: April 29, 2004
    Applicant: Biostream, Inc.
    Inventors: John W. Babich, Kevin P. Maresca
  • Compounds for targeting and imaging infection and inflammation
    Patent number: 6491893
    Abstract: The present invention provides novel agents for specifically targeting and detecting or treating focal sites of infection or inflammation in a subject.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: December 10, 2002
    Assignee: Biostream, Inc.
    Inventor: John W. Babich
  • Fatty acid analogs for diagnosis of coronary artery disease
    Patent number: 6437103
    Abstract: Radioimaging agents, which exhibit high uptake and retention in the myocardium are disclosed.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: August 20, 2002
    Assignee: Biostream Inc.
    Inventors: John W. Babich, Kevin Maresca, Timothy Shoup, David R. Elmaleh
  • Matrices for drug delivery and methods for making and using the same
    Patent number: 6395299
    Abstract: In one aspect, biocompatible matrices such as sol-gels encapsulating a reaction center may be administered to a subject for conversion of prodrugs into biologically active agents. In certain embodiments, the biocompatible matrices of the present invention are sol-gels. In one embodiment, the enzyme L-amino acid decarboxylase is encapsulated and implanted in the brain to convert L-dopa to dopamine for treatment of Parkinson's disease.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: May 28, 2002
    Assignee: Biostream, Inc.
    Inventors: John W. Babich, Jon Zubieta, Grant Bonavia
  • Meta substituted arylalkylamines and therapeutic and diagnostic uses therefor
    Patent number: 6313175
    Abstract: Novel meta substituted arylalkylamine compounds are disclosed. These compounds can be administered as small molecule drugs to treat diseases or conditions associated with insufficient serotonin mediated nerve transmission (e.g., depression and obesity).
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: November 6, 2001
    Assignee: Biostream, Inc.
    Inventors: David R. Elmaleh, Alan J. Fischman