Patents Assigned to Biostream Therapeutics, Inc.
  • Imaging agents for diagnosis of Parkinson's disease
    Patent number: 6677454
    Abstract: Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagnosis of Parkinson's disease. Another aspect of the present invention relates to piperidine monoamine transporter ligands, comprising a functional group capable of chelating a radionuclide, e.g., technetium, and methods of use thereof.
    Type: Grant
    Filed: January 28, 2003
    Date of Patent: January 13, 2004
    Assignee: Biostream Therapeutics, Inc.
    Inventors: John W. Babich, Miles P. Smith
  • Imagining agents for diagnosis of Parkinson's disease
    Patent number: 6515131
    Abstract: Generally, the present invention is directed to central nervous system dopamine transporter-imaging agents and methods of use thereof. In certain embodiments, the present invention relates to radiolabeled piperidine derivatives for use as imaging agents in the diagnosis of Parkinson's disease. Another aspect of the present invention relates to piperidine monoamine transporter ligands, comprising a functional group capable of chelating a radionuclide, e.g., technetium, and methods of use thereof.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: February 4, 2003
    Assignee: Biostream Therapeutics, Inc.
    Inventors: John W. Babich, Miles P. Smith
  • Analogs of cocaine
    Patent number: 6180648
    Abstract: The invention provides a compound of formula (I): wherein R1, R2, R3, and Y have any of the meanings defined in the specification; as well a pharmaceutical composition comprising a compound of formula I; intermediates and methods useful for preparing a compound of formula I; and therapeutic methods for treating drug addiction, Parkinson's disease or depression comprising administering a compound of formula I, to a mammal in need of such treatment.
    Type: Grant
    Filed: April 7, 1998
    Date of Patent: January 30, 2001
    Assignee: Biostream Therapeutics, Inc.
    Inventors: Alan P. Kozikowski, Gian Luca Araldi