Patents Assigned to Biosurface Technology, Inc.
  • Cryopreservation of cultured epithelial sheets
    Patent number: 5145770
    Abstract: Disclosed is a method of cryopreserving a sheet of living, cultured epithelial cells for use as a skin wound dressing. The method ensures that the integrity of the sheet will be maintained, and it preserves a significant number of cells in a mitotically competent, physiologically healthy form. It involves use of a non cell penetrating cryoprotectant and certain freezing and thawing conditions.
    Type: Grant
    Filed: June 4, 1990
    Date of Patent: September 8, 1992
    Assignee: BioSurface Technology, Inc.
    Inventors: Ross A. Tubo, Susan F. Schaeffer, Alexander Schermer, Richard Odessey
  • Cool storage of cultured epithelial sheets
    Patent number: 5100676
    Abstract: The viability of cohesive sheets of cultured epithelial cells such as keratinocytes used as wound dressings is maintained or improved by storage at a temperature within the range of 8.degree.-25.degree. C., preferably 13.degree.-23.degree. C., for periods greater than 8 hours, preferably up to 26 hours. This method and the resulting product permits a significant increase in the shipping radius of cultured dressings manufactured in a central facility, and increases flexibility in scheduling of shipments and surgical procedures.
    Type: Grant
    Filed: February 2, 1990
    Date of Patent: March 31, 1992
    Assignee: Biosurface Technology, Inc.
    Inventors: Richard Odessey, Alexander Schermer, Susan F. Schaeffer, Ross A. Tubo
  • Container for storage and distribution of a skin wound dressing
    Patent number: 5040677
    Abstract: Disclosed is a container for the storage and distribution of a cultured epithelial, generally planar, living, skin wound dressing that allows the dressing to be gently removed by lifting perpendicular to a support surface in the container. The design minimizes handling of the graft dressing thereby promoting cell viability.
    Type: Grant
    Filed: June 4, 1990
    Date of Patent: August 20, 1991
    Assignee: Biosurface Technology, Inc.
    Inventors: Ross A. Tubo, Richard Odessey