Abstract: The present invention relates to a sorbent for extracting polar components from a sample where the sorbent comprises a cross-linked polymer comprising nitrogen containing cyclic compounds, for example 1-vinylimidazole and/or 4-vinylpyridine. The invention further relates to a method of producing said sorbent and the use of the sorbent.

Abstract: The present invention relates to a mesoporous polymeric separation material comprising one or more functional groups bound to metal ions from Cu, Zn, Ag, or Pd. Methods of producing the material, as well as methods for its preparation, and use of said material in separation of pesticides from food or feed products is disclosed.

Abstract: The present invention relates to a method for extracting acrylamide from a matrix comprising matrix components and acrylamide, comprising the steps: bringing said matrix in contact with water to obtain an aqueous extract, and, optionally, adding a base to the aqueous extract; loading a portion of the aqueous extract obtained in the previous step onto an inert support; allowing the inert support to absorb the aqueous extract; extracting acrylamide from the aqueous extract by passing a water immiscible organic solvent through the inert support; thereby obtaining an organic extract. It further relates to a method for analyzing acrylamide content in a matrix comprising matrix components and acrylamide.

Abstract: The present invention relates to laboratory instruments, in particular to instruments for automated preparation of liquid samples like Solid Phase Extraction (SPE), Supported Liquid Extraction (SLE) or liquid-liquid extraction (LLE). The instrument reduces the risk of cross-contamination between sample collection containers by lifting the sample collection containers to the level of the outlet of the sample processing containers, or slightly above. The instrument further comprises a movable table positioning the liquid collection containers directly beneath said sample processing containers and a waste collection container directly beneath the sample processing containers, wherein said waste collection container is vertically movable from a position below the movable table to a position above the movable table.

Abstract: The present invention relates to an apparatus and methods for performing chemical reactions. In particular, the present invention relates to an apparatus for heating chemical reaction mixtures. The apparatus applies one or more semiconductor based microwave generators making the apparatus suitable for parallel processing of chemical reaction mixtures. The invention further relates to methods for performing chemical reactions, e.g. methods for heating a plurality of samples simultaneously or sequentially, methods for monitoring a microwave heated chemical reaction, and methods where the optimum conditions with respect to parameters, such frequency and applied power can be determined for the system consisting of apparatus plus sample.

Abstract: Provided are methods and apparatus for determining conditions for performing chromatography, particularly flash chromatography. The methods may be utilized for separating compounds in a sample in a column chromatography system. The method includes determining at least two retention factors corresponding to the TLC performance of a target compound and an adjacent compound and defining a sample loading amount and a solvent gradient profile using at least two solvents that will result in differential elution of the target and adjacent compounds from a chromatography column. The chromatography system and loading parameters may be selected to provide satisfactory separation of the target compound from adjacent compounds.

Abstract: A micro vial assembly for performing microwave-assisted chemical reactions on small reaction mixture volumes is disclosed, wherein a reaction vessel (10) is sealed through a diaphragm (30) that is capped over an open end of the reaction vessel. The reaction vessel mouths in an end plane of a sleeve (20) surrounding the reaction vessel, the diaphragm being clamped for sealing the open end of the vessel by means of a cap (40) which is secured to the sleeve. The sleeve provides a radial extension of the reaction vessel in order to bridge the radial distance between a wall of the reaction vessel and other components in a system for performing microwave-assisted chemical reactions.

Abstract: The present application relates to an affinity material useful in antibody purification.

Abstract: The present invention relates to a polymer bead material that are characterised by having pore sizes that can be pre-determined and that can be obtained with a narrow distribution of such pore sizes created by use of sacrificial filler materials within the polymer material. The invention also discloses processes for production of the material as spherical or approximately spherical beads or resins with predefined sizes. Also, the invention relates to the preparation of molecularly imprinted polymer materials that are created by the said method. Further the invention relates to the use of said polymer materials for separation, detection, catalysis or entrapment of chemicals, metal ions, inorganic compounds, drags, peptides, proteins, DNA, natural and artificial polymers, natural or artificial compounds, food or pharma products, viruses, bacteria, cells and other entities.

Abstract: An embodiment of the present invention relates to a composite material including a hydrophobic porous organic polymer bead. An embodiment further relates to a method of obtaining the composite material as well as the use thereof.

Abstract: The present invention relates to molecularly imprinted polymers, methods for their preparation and use of said molecularly imprinted polymers in separation, chemical sensors, drug screening, catalysis and in regioselective and enantioselective synthesis.

Abstract: The present invention relates to a mesoporous polymeric separation material comprising one or more functional groups bound to metal ions from Cu, Zn, Ag, or Pd. Methods of producing the material, as well as methods for its preparation, and use of said material in separation of pesticides from food or feed products is disclosed.

Abstract: A chromatography column comprises a tubular member (1) having an open inlet end and an outlet end and being adapted to receive a packing material, and an end piece (2) inserted through the inlet end of the tubular member (1). The end piece (2) comprises a generally planar inner end portion 4, and a rounded outer end portion (5), adapted to accommodate pressure forces acting on the inner end. The end piece (2) is fixed to the inner surface of the tubular member (1) by a weld- or bond-forming joining technique based on non-contact energy transfer, preferably laser welding. A method for manufacturing a pre-packed chromatography column is also disclosed.

Abstract: A modified solid-support for use as a supported reagent for use in reduction reactions, including reductive amination comprising a solid-support having an tetrasubstituted ammonium cation species ionically bonded to a borohydride anion species extending therefrom having the general formula: wherein P is a solid-support, S is a spacer group selected from the group consisting of alkylene, {including —(CH2)n—}, alkyleneoxy {including -0(CH2)n—}, alkylenethio {including —S(CH2)n—} and alkylenecarboxy, {including —O(O)C—(CH2)n—}, n=2-16. R1, R2, R3 and R are each independently selected from the group consisting of alkyl, cycloalkyl, haloalkyl and aryl. Y equals 1, 2 or 3. H is hydrogen or deuterium.

Abstract: An embodiment of the present invention relates to a composite material including a hydrophobic porous organic polymer bead. An embodiment further relates to a method of obtaining the composite material as well as the use thereof.

Abstract: Devices and methods for performing microwave-assisted chemical synthesis including heterogeneous starting materials, comprising a reaction vessel (9), a microwave source (3) for generating microwave electromagnetic radiation, means for transporting microwave electromagnetic radiation (5) to said reaction vessel (9), at least one liquid reservoir (45) containing a liquid component, means for transporting a liquid component (43) from a liquid reservoir to said reaction vessel, wherein it further comprises an automated system for dispensing solid starting material (59) into said reaction vessel.

Abstract: Provided are methods and apparatus for determining conditions for performing chromatography, particularly flash chromatography. The methods may be utilized for separating compounds in a sample in a column chromatography system. The method includes determining at least two retention factors corresponding to the TLC performance of a target compound and an adjacent compound and defining a sample loading amount and a solvent gradient profile using at least two solvents that will result in differential elution of the target and adjacent compounds from a chromatography column. The chromatography system and loading parameters may be selected to provide satisfactory separation of the target compound from adjacent compounds.

Abstract: The present invention provides a method of identifying a base at a target position in a sample nucleic acid sequence, said method comprising: subjecting a primer hybridised to said sample nucleic acid immediately adjacent to the target position, to a polymerase primer extension reaction in the presence of a nucleotide, whereby the nucleotide will only become incorporated if it is complementary to the base in the target position, and determining whether or not said nucleotide is incorporated by detecting whether PPi is released, the identity of the target base being determined from the identity of any nucleotide incorporated, wherein, where said nucleotide comprises an adenine base, an ?-thio triphosphate analogue of said nucleotide is used, ant the Rp isomer of said analogue and/or the degradation products of said analogue are eliminated from the polymerase reaction step.

Abstract: A microwave heating device for heating load(s) and including a cylinder-shaped cavity enclosed by a periphery wall, the cavity is provided with a microwave feeding device. The heating device may have a dielectric wall structure arranged inside the cavity between the periphery wall and the load(s). The microwave feeding device may be arranged to generate a microwave field being an arch surface hybrid mode having TE and TM type properties inside the cavity to heat the load(s).

Abstract: The present invention provides a method of identifying a base at a target position in a sample nucleic acid sequence, said method comprising: subjecting a primer hybridised to said sample nucleic acid immediately adjacent to the target position, to a polymerase primer extension reaction in the presence of a nucleotide, whereby the nucleotide will only become incorporated if it is complementary to the base in the target position, and determining whether or not said nucleotide is incorporated by detecting whether Ppi is released, the identity of the target base being determined from the identity of any nucleotide incorporated, wherein, where said nucleotide comprises an adenine base, an ?-thio triphosphate analogue of said nucleotide is used, and the Rp isomer of said analogue and/or the degradation products of said analogue are eliminated from the polymerase reaction step.