Abstract: The present invention relates to a composition comprising at least one polypeptide, which polypeptide comprises the amino acid sequence set out in any one of SEQ ID NOs: 1 to 51 or 101 to 111 or an amino acid sequence having at least about 80% sequence identify thereto and which polypeptide is capable of binding to a fungus. The invention further relates to a composition comprising at least one polypeptide, which polypeptide comprises a CDR1 region having the amino acid sequence set out in any one of SEQ ID NOs: 52 to 67 or 112 to 122, a CDR2 region having the amino acid sequence set out in any one of SEQ ID NOs: 68 to 83 or 123 to 133, and a CDR3 region having the amino acid sequence set out in any one of SEQ ID NOs: 84 to 100 or 134 to 144 and which polypeptide is capable of binding to a fungus. The compositions may be used as anti-fungal compositions.
Type:
Grant
Filed:
April 25, 2023
Date of Patent:
September 24, 2024
Assignee:
Biotalys NV
Inventors:
Natalia Beloglazova, Hilde Adi Pierrette Revets, Patrick Stanssens, Inge Elodie Van Daele
Abstract: The present invention relates to a composition comprising at least one polypeptide, which polypeptide comprises the amino acid sequence set out in any one of SEQ ID NOs: 1 to 51 or 101 to 111 or an amino acid sequence having at least about 80% sequence identify thereto and which polypeptide is capable of binding to a fungus. The invention further relates to a composition comprising at least one polypeptide, which polypeptide comprises a CDR1 region having the amino acid sequence set out in any one of SEQ ID NOs: 52 to 67 or 112 to 122, a CDR2 region having the amino acid sequence set out in any one of SEQ ID NOs: 68 to 83 or 123 to 133, and a CDR3 region having the amino acid sequence set out in any one of SEQ ID NOs: 84 to 100 or 134 to 144 and which polypeptide is capable of binding to a fungus. The compositions may be used as anti-fungal compositions.
Type:
Grant
Filed:
April 25, 2023
Date of Patent:
May 28, 2024
Assignee:
Biotalys NV
Inventors:
Natalia Beloglazova, Hilde Adi Pierrette Revets, Patrick Stanssens, Inge Elodie Van Daele
Abstract: This disclosure relates to agrochemical and biological control compositions for combating pests, more specifically plant pests, comprising at least one polypeptide, which specifically binds to a pest. The disclosure further provides methods for protecting or treating a plant or a part of a plant from an infection or other biological interaction with a plant pathogen, at least comprising the step of applying directly or indirectly to a plant or to a part of a plant, an agrochemical composition, under conditions effective to protect or treat a plant or a part of a plant against a infection or biological interaction with a plant pathogen. Further provided are methods for producing such agrochemical compositions and formulations, to polypeptides with a specific pesticidal activity comprised within an agrochemical formulation, to nucleic acids encoding such polypeptide and to plants comprising chimeric genes comprising such nucleic acids.
Type:
Grant
Filed:
July 31, 2019
Date of Patent:
June 8, 2021
Assignee:
Biotalys NV
Inventors:
Peter Verheesen, Chris De Jonghe, Inge Elodie Van Daele, Miguel Francesco Coleta De Bolle, João Filipe Veloso Vieira, Karin Thevissen, Bruno Cammue
Abstract: This disclosure relates to a transgenic plant or plant tissue or plant cell comprising at least one polynucleotide encoding a polypeptide comprising a variable domain of a heavy-chain antibody (VHH) specifically binding to a sphingolipid of a fungus. This disclosure further relates to a method for protecting at least part of a plant, plant tissue or plant cell from an infection with a plant pathogen, for inhibiting the growth of a plant pathogen on at least part of a plant, plant tissue or plant cell, or for increasing pathogen resistance of at least part of a plant, plant tissue or plant cell.
Type:
Grant
Filed:
November 5, 2015
Date of Patent:
December 8, 2020
Assignee:
BIOTALYS
Inventors:
Peter Verheesen, Jan Geerinck, João Filipe Veloso Vieira, Marnix Peferoen, Inge Elodie Van Daele