Abstract: The acylated enamide compounds are acylated enamides corresponding to the general formula ##STR1## in which Z represents an electron donor group,n is 1, 2 or 3, andR.sup.1 represents hydrogen, a halogen or any organic group,or salts, complexes, alkylated derivatives or acylated derivatives of these compounds.Typical acylated enamide compounds according to the invention correspond to the formula ##STR2## These acylated enamide compounds and the pharmaceutical compositions containing the compounds are useful in the prevention and treatment of cancers.