Patents Assigned to Biotechnology Foundation, Inc.
  • Engineered biomass with increased oil production
    Patent number: 9574206
    Abstract: The present invention relates to a genetically modified plant having an increased amount of oil in its green biomass as compared to the oil in the green biomass of its non-genetically modified counterpart. The plants may be used for producing bio-fuels such as biodiesel fuel.
    Type: Grant
    Filed: August 5, 2014
    Date of Patent: February 21, 2017
    Assignees: Biotechnology Foundation, Inc., Thomas Jefferson University
    Inventors: Hilary Koprowski, Vyacheslav Andrianov, Mykola Borysyuk
  • Engineered tobacco biomass with increased oil production
    Patent number: 8847010
    Abstract: The present invention relates to a genetically modified plant having an increased amount of oil in its green biomass as compared to the oil in the green biomass of its non-genetically modified counterpart. The plants may be used for producing bio-fuels such as biodiesel fuel.
    Type: Grant
    Filed: June 12, 2008
    Date of Patent: September 30, 2014
    Assignees: Biotechnology Foundation, Inc., Thomas Jefferson University
    Inventors: Hilary Koprowski, Vyacheslav Andrianov, Mykola Borsyuk
  • Production of cancer-specific antibodies in plants
    Publication number: 20090041776
    Abstract: The invention as described herein provides compositions and methods for cancer immunotherapy and cancer detection. In particular, the invention discloses plant-derived human monoclonal antibodies that bind human carcinoma antigens in cancer cell lines.
    Type: Application
    Filed: April 23, 2008
    Publication date: February 12, 2009
    Applicants: Biotechnology Foundation, Inc., The Chancellor, Masters and Scholars of the University of Oxford, University of Oxford
    Inventors: Hilary Koprowski, Kisung Ko, Pauline Rudd, Yoram Tekoah, Raymond Dwek
  • Production of rabies antibodies in plants
    Publication number: 20060134099
    Abstract: Human rabies monoclonal antibodies (rabies MAbP) comprising rabies human MAb S057 heavy chain and light chain subunits are expressed and assembled in plants under the control of two strong constitutive promoters. Additionally, regulatory control elements such as alfalfa mosaic virus untranslated leader sequence and Lys-Asp-Glu-Leu (KDEL) endoplasmic reticulum retention signal were linked at the N- and C-terminus of the heavy chain of human rabies MAbP, respectively to regulate expression of the rabies MAbP. Rabies MAbP was as effective at neutralizing the activity of the rabies virus as the mammalian-derived antibody (MAbM) or human rabies immunoglobulin (HRIG).
    Type: Application
    Filed: June 2, 2004
    Publication date: June 22, 2006
    Applicants: BIOTECHNOLOGY FOUNDATION, INC., UNIVERSITY OF OXFPRD
    Inventors: Hilary Koprowski, Kisung Ko, Pauline Rudd, Raymond Dwek, Yoram Tekoah
  • Production of cancer-specific antibodies in plants
    Publication number: 20050138692
    Abstract: The invention as described herein provides compositions and methods for cancer immunotherapy and cancer detection. In particular, the invention discloses plant-derived human monoclonal antibodies that bind human carcinoma antigens in cancer cell lines.
    Type: Application
    Filed: June 2, 2004
    Publication date: June 23, 2005
    Applicants: Biotechnology Foundation, Inc., The Chancellor, Masters and Scholars of the University of Oxford, University of Oxford
    Inventors: Hilary Koprowski, Kisung Ko, Pauline Rudd, Yoram Tekoah, Raymond Dwek