Abstract: Mixing device (1) and fluid mixing method, by means of successive transfers between syringes. The mixing method comprises placing a pair of syringes (2, 3) in the mixing device (1), adjusting a variable fixing element adaptable to the pair of syringes (2, 3) and selecting and running a mixing programme, being the mixing force, the speed and the range and the number of transfers adjustable. The mixing device comprises a mobile carriage (7) longitudinally movable and fixing elements (8, 9) with an adjustable distance between them. The invention allows for the mixing or emulsifying of blood fluids with different viscosity, particularly a protein gel and a platelet-rich plasma, for the preparation of dermatological formulations, in a versatile, hygienic and effective manner.

Abstract: A formulation, or tissular adhesive, obtained from a platelet-rich blood composition and/or growth factors, and method for the preparation of this adhesive. The preparation method of the adhesive comprises the steps of raising the temperature of the initial blood composition and subsequently activating the composition. Among other advantages, the tissular adhesive is biocompatible and biodegradable, has desirable biological or medical properties provided by the presence of platelets or growth factors, and also has a high adhesiveness and an accelerated coagulation process.

Abstract: A device for the extraction of blood or a blood compound is provided that includes a tube, a piston assembly, a handle assembly that can be clipped to the piston assembly, and a perforable sealing element that prevents the flow of fluid from a sealed interior space of the tube towards a longitudinal interior cavity of the handle assembly located adjacent to a separable area of the handle assembly. In use, the handle assembly is pushed to the bottom of the tube, causing the handle assembly to be clipped to the piston assembly, the handle assembly and the piston assembly are then moved rearwards forming a vacuum in the space, the piston assembly is clipped to an end cap of the tube and the gripping portion of the handle assembly is separated, obtaining a vacuum container with a perforable closure.

Abstract: Formulation comprising, or derived from, an initial blood composition, wherein the formulation is rich in platelets and/or growth factors and proteins originating from the initial blood composition, and wherein the proteins are in a gelled state. The invention also refers to method for preparing the formulation, comprising the steps of heating and then cooling the initial blood composition at certain temperatures and times. Among other advantages, the formulation in accordance with the invention is biocompatible and biodegradable, presents the desirable biological or medical properties provided by the presence of platelets or growth factors, and also presents high dimensional stability over time.

Abstract: Wrench (1) for providing a maximum torque to an external part, characterized in that it comprises at least one elongated metal part (3) provided with a fixed end (4) and a pusher end (5), and which also comprises a torque-applying head (6) upon which the pusher end (5) acts, wherein the elongated metal part (3) is capable of bending when a torque is applied with the wrench, and wherein the elongated metal part (3) reaches a maximum bending point that determines the maximum torque provided by the wrench (1). The inventive wrench (1) is easier to use than conventional spring-based wrenches as the force required to adjust the torque is minimal and independent of the torque value to which the wrench is adjusted. It is also capable of providing higher torque values.

Abstract: Device (1a, 1b, 1c, 1d; 40) for extracting, storing and/or processing blood or other substances of human or animal origin, and for applying blood compounds or other biological compounds, which comprises a body (2; 41) inside which a piston (3; 42) is capable of moving longitudinally and is separable at least in part, where the body (2; 41) is provided with an internal space (9; 51) that may be connected to the outside by means of a conduit (6; 50) at a first end (4; 48) of the body (2; 41), where the body (2; 41) and the piston (3; 43) may be blocked longitudinally in at least one position to allow the creation of different degrees of vacuum. The device has multiple uses and is extremely versatile.

Abstract: Implant removal tool (1) which allows removing an implant (5) from a patient's bone (6). The implant removal tool (1) comprises a head (2), to which a torque-providing system is attached, and a threaded body (4) preferably with a decreasing diameter. The threaded body (4) preferably has a thread to the left and is intended to be threaded into the hole (7) of the implant (5). The extraction of the implant (5) is relatively simple to carry out, removing the implant (5) in an almost clean manner and leaving a very small cavity (13) in the patient's bone (6). Therefore, the implant removal tool (1) according to the invention makes the removal of an implant (5) a far less traumatic procedure for the patient.

Abstract: A trephine drill bit comprising a body and a tip connected to the body, wherein the tip includes a reduced area having a smaller diameter than the body, the reduced area ending in a stop to indicate when the trephine drill bit should no longer be introduced. A method is also disclosed.

Abstract: A tool for drilling bone tissue, which has the advantage of having a cutting tip with a flat effective shape that prevents perforation of the Schneider membrane or injury to the dental nerve when drilling close to them. The tool is disposed along an longitudinal axis and includes a non-cutting main body, a narrowed area for retaining bone and a cutting tip, which includes cutting blades, each one of which is provided with a front cutting edge substantially perpendicular to the longitudinal axis and a substantially lateral cutting edge that forms an angle of between 0 and 10° with the longitudinal axis. Spaces for receiving bone are disposed between the cutting blades and are connected to the narrowed area.

Abstract: The invention relates to an implant for the human or animal body, which on its outer surface comprises at least one calcium salt that is soluble in a polar liquid. The invention also refers to various methods for the preparation of the preceding implant. The calcium ions contained on the surface of the implant provide said surface with four chemically and biologically advantageous properties: hydrophilicity, protection against atmospheric contamination, a pro-coagulant property and a pro-mineralizing property.

Abstract: Metal structure that serves as an internal support to a dental prosthesis, comprising at least two support posts (1) designed to be attached on respective dental implants (10), and at least one rod (3) for connecting two adjacent support posts (1), where at least one support post (1) comprises at least one protruding element (4a, 4b) that projects from its side, and at least one rod (3) that comprises a first end (5) provided with a blind hole (6) designed to receive a first protruding element (4a) of a support post (1), thus providing an articulated connection that acts like a ball joint, and a longitudinal recess (7) designed to receive a second protruding element (4b) of the adjacent support post (1). This structure is easy to prepare and to assemble.

Abstract: Method for extracting an implant installed in a bone, which comprises the application of a torque on an extraction tool in order to thread it in the interior of the implant until the implant-bone connection is broken, with the specific feature that the torque is applied in phases. In each phase a torque that is increasingly greater than in the previous phase is applied and the application of torque is then eased. This method brings about a gradual and controlled deformation of the head of the implant, with the result that the extraction tool is inserted more deeply into the implant. As a result, higher breakage torques may be applied without damage being caused to the extraction tool.

Abstract: Wrench (1) for providing a maximum torque to an external part, characterised in that it comprises at least one elongated metal part (3) provided with a fixed end (4) and a pusher end (5), and which also comprises a torque-applying head (6) upon which the pusher end (5) acts, wherein the elongated metal part (3) is capable of bending when a torque is applied with the wrench, and wherein the elongated metal part (3) reaches a maximum bending point that determines the maximum torque provided by the wrench (1). The inventive wrench (1) is easier to use than conventional spring-based wrenches as the force required to adjust the torque is minimal and independent of the torque value to which the wrench is adjusted. It is also capable of providing higher torque values.

Abstract: A method for producing a porous calcium polyphosphate structure, which comprises the steps of mixing monocalcium phosphate (MCP) with silicic acid, and sintering the mixture at a predefined temperature or temperatures for a predefined time, after which the porous calcium polyphosphate is obtained. The method allows a porous biomaterial with a controllable porosity to be obtained, and which also has the ability to activate the platelets in a plasma rich in platelets and cause the release of growth factors from the platelets.

Abstract: Method for the preparation of at least one compound with biological properties from blood, where said method is performed in sealed tubes at a pressure below atmospheric pressure, thereby reducing or preventing the bacterial contamination of the compound through handling. The method comprises the repetition, for as many times as is required, of the following steps: connecting a second container that is vacuum-sealed to an extraction device connected in turn to a first container that contains blood separated into fractions, waiting for a period of time until the required fraction(s) is/are transferred, and removing said second container, with it thus being possible to obtain several second containers with different compounds for different medical applications including biological therapies. The steps may be performed in a closed system, without removing the caps of the containers, or alternatively the first container may be opened prior to the introduction of the extraction device.

Abstract: The invention relates to an implant for the human or animal body, which on its outer surface comprises at least one calcium salt that is soluble in a polar liquid. The invention also refers to various methods for the preparation of the preceding implant. The calcium ions contained on the surface of the implant provide said surface with four chemically and biologically advantageous properties: hydrophilicity, protection against atmospheric contamination, a pro-coagulant property and a pro-mineralising property.

Abstract: The invention relates to an implant for the human or animal body, which on its outer surface comprises at least one calcium salt that is soluble in a polar liquid. The invention also refers to various methods for the preparation of the preceding implant. The calcium ions contained on the surface of the implant provide said surface with four chemically and biologically advantageous properties: hydrophilicity, protection against atmospheric contamination, a pro-coagulant property and a pro-mineralising property.

Abstract: An adapter device (1) for reducing or eliminating the potential bacterial contamination in a process of extraction or transfer of blood components from at least one container (3) to a recipient or any applicable destination, thereby increasing user safety, that comprises a body (2) provided with at least one first area (2a) designed to be approached or attached to at least one container (3) and at least one second area (2b) designed to remain accessible to the exterior, and at least one needle (7) that projects from each first area (2a) and is capable of piercing a pierceable area (3a) of a container (3). The needle (7) presents an inner tube (8) that communicates with an inner tube (9) of the body (2), which in turn leads to an opening (4) in a second area (2b), and at least one flexible part (10) that maintains each inner tube (9) of the body (2) closed.

Abstract: Method for the preparation of at least one compound with biological properties from blood, where said method is performed in sealed tubes at a pressure below atmospheric pressure, thereby reducing or preventing the bacterial contamination of the compound through handling. The method comprises the repetition, for as many times as is required, of the following steps: connecting a second container that is vacuum-sealed to an extraction device connected in turn to a first container that contains blood separated into fractions, waiting for a period of time until the required fraction (s) is/are transferred, and removing said second container, with it thus being possible to obtain several second containers with different compounds for different medical applications including biological therapies. The steps may be performed in a closed system, without removing the caps of the containers, or alternatively the first container may be opened prior to the introduction of the extraction device.

Abstract: Metal structure that serves as an internal support to a dental prosthesis, comprising at least two support posts (1) designed to be attached on respective dental implants (10), and at least one rod (3) for connecting two adjacent support posts (1), where at least one support post (1) comprises at least one protruding element (4a, 4b) that projects from its side, and at least one rod (3) that comprises a first end (5) provided with a blind hole (6) designed to receive a first protruding element (4a) of a support post (1), thus providing an articulated connection that acts like a ball joint, and a longitudinal recess (7) designed to receive a second protruding element (4b) of the adjacent support post (1). This structure is easy to prepare and to assemble.