Patents Assigned to BIOTHLON, INC.
  • Publication number: 20190204294
    Abstract: A method of manufacturing and using a nanofluidic NAND transistor sensor array scheme including a plurality of nanopore channel pillars, a plurality of respective fluidic channels, a plurality of gate electrodes, a top chamber, and a bottom chamber includes placing a sensor substrate in an electrolyte solution comprising biomolecules and DNA. The method also includes placing first and second electrodes in the electrolyte solution (Vpp and Vss of the nanofluidic NAND transistor); forming the nanopore channel pillars; placing the gate electrodes and gate insulators in respective walls of the nanopore channel pillars; applying an electrophoretic bias in the first and second electrodes; applying a bias in the gate electrodes; detecting a change in an electrode current in the electrolyte solution caused by a change in a gate voltage; and detecting a change in a surface charge in nanopore channel electrodes in the respective fluidic channels.
    Type: Application
    Filed: December 31, 2018
    Publication date: July 4, 2019
    Applicant: BIOTHLON, INC.
    Inventors: Kyung Joon Han, Jungkee Yoon
  • Publication number: 20190101524
    Abstract: A 3D nanopore device for characterizing biopolymer molecules includes a first selecting layer having a first axis of selection. The device also includes a second selecting layer disposed adjacent the first selecting layer and having a second axis of selection orthogonal to the first axis of selection. The device further includes an third electrode layer disposed adjacent the second selecting layer, such that the first selecting layer, the second selecting layer, and the third electrode layer form a stack of layers along a Z axis and define a plurality of nanopore pillars.
    Type: Application
    Filed: September 28, 2018
    Publication date: April 4, 2019
    Applicant: BIOTHLON, INC.
    Inventors: Kyung Joon Han, Jungkee Yoon