Patents Assigned to BIOTUBE CO., LTD.
  • Publication number: 20230270574
    Abstract: Disclosed is an intravascular indwelling stent that include a stent main body and a polymer film covering the stent main body. Through-holes are formed in the polymer film. The through-holes connect an inside and an outside of a cylinder of the intravascular indwelling stent to each other and each have an opening size of 0.02 mm or more and 0.2 mm or less. An opening occupancy, which is the ratio of the opening area of all the through-holes included in a unit area of the outer surface of the polymer film to the unit area, is 25% or more and 41% or less. A surface density of boundary, which is the ratio of the length of opening edges of all the through-holes included in a unit area of the outer surface of the polymer film to the unit area, is 9.5/mm or more and 30/mm or less.
    Type: Application
    Filed: July 15, 2021
    Publication date: August 31, 2023
    Applicant: BIOTUBE CO., LTD
    Inventors: Yasuhide NAKAYAMA, Hisashi SUGIURA, Takaharu TANAKA
  • Publication number: 20230235291
    Abstract: This invention relates to a tissue construct comprising a core portion having a recess and composed of fibrous connective tissue, and loose fibrous somatic stem cell-accumulated tissue comprising type III collagen and somatic stem cells which is formed in the recess; a device for producing the same; and a method for collecting somatic stem cells from the tissue construct.
    Type: Application
    Filed: May 28, 2021
    Publication date: July 27, 2023
    Applicant: BIOTUBE CO., LTD.
    Inventors: Yasuhide NAKAYAMA, Yasushi SATO, Ryosuke IWAI, Masanori FUKUSHIMA, Hiroshi TAKENAKA
  • Publication number: 20220257362
    Abstract: In a connective-tissue body according to an embodiment of the present disclosure, comprising a biological tissue including collagen, a fine surface layer formed more finely than the inside thereof is provided on the surface of the connective-tissue body.
    Type: Application
    Filed: July 10, 2020
    Publication date: August 18, 2022
    Applicant: BIOTUBE CO., LTD.
    Inventors: Yasuhide NAKAYAMA, Yasushi SATO, Takeshi TERAZAWA
  • Publication number: 20190201583
    Abstract: The present invention provides a method for forming a connective tissue body, which enables extending the ranges of design values in terms of shape, dimension, etc., of the connective tissue body. This method comprises: a fat treatment step for removing fat contained in a connective tissue body, which is formed in an environment where a biological tissue material is present, from the interior of the connective tissue body while the connective tissue body is being set in a molding tool, and for causing the shape of the connective tissue body to follow the shape of the molding tool; and a bioinert solution treatment step for immersing the connective tissue body, together with the molding tool, in a bioinert solution while the connective tissue body is being shaped so as to follow the shape of the molding tool after the fat treatment step.
    Type: Application
    Filed: August 30, 2017
    Publication date: July 4, 2019
    Applicants: BIOTUBE CO., LTD., NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER
    Inventors: Yasuhide NAKAYAMA, Takeshi MORIWAKI, Tomonori OIE