Patents Assigned to Biovectra Inc.
  • Patent number: 9808011
    Abstract: Disclosed herein is a PEGylated bis pentacyclic triterpene, compositions comprising the PEGylated bis pentacyclic triterpene, methods of preparing the PEGylated bis pentacyclic triterpene, and a method of treating or preventing a fungal disease in a plant using the compounds and compositions disclosed herein. The PEGylated bis pentacyclic triterpene has the formula A-P-B, wherein A is a first pentacyclic triterpene; B is a second pentacyclic triterpene; and P is a polyethylene glycol (PEG) molecule.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: November 7, 2017
    Assignee: BIOVECTRA INC.
    Inventors: John G. Riley, Richard J. Bethell
  • Patent number: 8222039
    Abstract: A process for purification of water soluble polymers is provided. A polymer of interest can be separated from a mixture of polymers, provided the polymer of interest differs from other polymers in the mixture in the number of reactive terminal groups. The process involves derivatizing polymers at the reactive terminal groups with a derivatizing molecule, bearing either (i) two or three cationic or anionic ionizable groups, and a group capable of covalent bonding to the reactive terminal groups or (ii) three or four ionizable groups, at least one of which is capable of covalent bonding to the reactive terminal groups; followed by ion exchange. The process allows removal of PEG from MPEG, and can be used for polymers having an average size greater than 9,000 Da Derivatization may be reversible in order to allow re-use of recovered contaminant polymers.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: July 17, 2012
    Assignee: Biovectra Inc.
    Inventors: James F. Monthony, Li Yang, Kurt E. Kershaw, Christopher D. Winslow, John G. Riley
  • Publication number: 20100323452
    Abstract: A process for purification of water soluble polymers is provided. A polymer of interest can be separated from a mixture of polymers, provided the polymer of interest differs from other polymers in the mixture in the number of reactive terminal groups. The process involves derivatizing polymers at the reactive terminal groups with a derivatizing molecule, bearing either (i) two or three cationic or anionic ionizable groups, and a group capable of covalent bonding to the reactive terminal groups or (ii) three or four ionizable groups, at least one of which is capable of covalent bonding to the reactive terminal groups; followed by ion exchange. The process allows removal of PEG from MPEG, and can be used for polymers having an average size greater than 9,000 Da Derivatization may be reversible in order to allow re-use of recovered contaminant polymers.
    Type: Application
    Filed: February 22, 2007
    Publication date: December 23, 2010
    Applicant: BIOVECTRA INC.
    Inventors: James F. Monthony, LI Yang, Kurt E. Kershaw, Christopher D. Winslow, John G. Riley