Patents Assigned to BIOWA, INC.
  • Methods of reducing basophil levels
    Patent number: 9815895
    Abstract: The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: November 14, 2017
    Assignees: BIOWA, INC., ASTRAZENECA AB
    Inventors: Masamichi Koike, George L. Spitalny, Alistair Wheeler, Barbara White
  • Methods Of Reducing Eosinophil Levels
    Publication number: 20140004109
    Abstract: The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung.
    Type: Application
    Filed: July 3, 2013
    Publication date: January 2, 2014
    Applicants: Medlmmune, LLC, Biowa, Inc.
    Inventors: Masamichi Koike, George L. SPITALNY, Alistair WHEELER, Barbara WHITE
  • Methods of reducing eosinophil levels
    Patent number: 8501176
    Abstract: The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: August 6, 2013
    Assignees: MedImmune, LLC, BIOWA, Inc.
    Inventors: Masamichi Koike, George L. Spitalny, Alistair Wheeler, Barbara White
  • Methods Of Reducing Eosinophil Levels
    Publication number: 20120148575
    Abstract: The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e.g. esophagus, stomach, small intestine and colon), or lung.
    Type: Application
    Filed: July 6, 2011
    Publication date: June 14, 2012
    Applicants: BIOWA, INC., Medlmmune, LLC
    Inventors: Masamichi Koike, George L. Spitalny, Alistair Wheeler, Barbara White
  • METHODS OF REDUCING EOSINOPHIL LEVELS
    Publication number: 20100291073
    Abstract: The present invention relates to a method of reducing the numbers of eosinophils in a human subject comprising administration to a subject an IL-5R binding molecule that comprises (a) a region that specifically binds to the IL-5R and (b) an immunoglobulin Fc region. In a specific embodiment, a method of the invention reduces the number of eosinophils in blood, bone marrow, gastrointestinal tract (e g, esophagus, stomach, small intestine and colon), or lung.
    Type: Application
    Filed: May 14, 2008
    Publication date: November 18, 2010
    Applicants: MEDIMMUNE, LLC, BIOWA, INC.
    Inventors: Masamichi Koike, George L. Spitalny, Alistair Wheeler, Barbara White