Patents Assigned to Bioware, Inc.
  • METHOD AND SYSTEM FOR THE AUTOMATIC DETECTION AND DIAGNOSIS OF A CANCER STEM CELL
    Publication number: 20100240087
    Abstract: A method for predetermining whether a cancer has a probability to become metastatic or recurrent, having the steps of: obtaining a sample cell population; assaying the sample cell population; detecting the rate of change of the sample cell population's pH over time; and comparing the pH change versus a predetermined pH rate of change. Also provided is a method of treating a patient having the steps of: isolating a cancer stem cell from a patient; culturing the cancer stem cell to produce a pool of descendant cells; culturing cells from the pool of descendant cells in the presence at least one compound among: anti-cancer drugs, myeloablative, chemotherapeutic, and immunotherapeutic agents, and a combination thereof; assaying over time, during the step of culturing, hydrogen ion concentration in the set of cells; and selecting a candidate therapeutic regimen for the patient based on a result of the assaying step.
    Type: Application
    Filed: March 20, 2009
    Publication date: September 23, 2010
    Applicant: Simbiosys Biowares, Inc.
    Inventors: Swati Bhattacharyya, Supratik Mukhopadhyay, Debashis Bhattacharya
  • Force sensitive handle for hand operated implement
    Patent number: 5502861
    Abstract: An improved handle for a hand operated implement of the type for which it is desirable to control the force of application. The handle has bifurcated sections which are connected by a means for sensing the applied force and indicating a variation of the applied force from a desired level.
    Type: Grant
    Filed: February 1, 1994
    Date of Patent: April 2, 1996
    Assignee: Bioware, Inc.
    Inventors: Eric L. Spieler, Richard M. Berman
  • Force sensitive handle for hand operated implement
    Patent number: 5282291
    Abstract: An improved handle for a hand operated implement of the type for which it is desirable to control the force of application. The handle has bifurcated sections which are connected by a means for sensing the applied force and indicating a variation of the applied force from a desired level.
    Type: Grant
    Filed: September 16, 1992
    Date of Patent: February 1, 1994
    Assignee: Bioware Inc.
    Inventors: Eric L. Spieler, Richard M. Berman
  • Process for gel cutting
    Patent number: 4051752
    Abstract: A process and a gel cutting device constructed and adapted to remove gel like material from a surface, the device having a hollow body with fluid communication therethrough, a pickup conduit attached to the inlet of the body, a cutter on the inlet end of the pickup conduit. The outlet of the body is connectable to a vacuum source. In operation the process and the gel cutter have the cutter of the pickup conduit passed into gel material, cutting same and passing the removed material through the pickup conduit into the hollow body.
    Type: Grant
    Filed: October 20, 1975
    Date of Patent: October 4, 1977
    Assignee: Bioware, Inc.
    Inventor: Leo P. Cawley