Abstract: The invention relates to a method for producing hydrophilic monomers which are particularly useful for electrophoresis and to electrophoresis compositions and coating compositions. The electrophoresis gel compositions and electrophoresis polymer compositions are hydrolytically stable and have high resolution. The method uses the steps of reacting a (meth)acryloyl with an aminoalcohol in the presence of a base in a polar solvent, optionally filtering an aqueous solution of the reaction product, deionizing an aqueous solution of the reaction product, and removing the solvent.
Type:
Grant
Filed:
July 29, 1999
Date of Patent:
October 15, 2002
Assignee:
BioWhittaker Molecular Applications, Inc.
Inventors:
Tianhong Zhang, Noriko Kusukawa, Mark Garner
Abstract: The present invention discloses the use of quaternary compounds as stabilizing agents for highly-sensitive fluorescent nucleic acid stains in aqueous solvents, their use in gels to give increased usable shelf life, and in compositions of solvents, providing ready-to-use stain solutions.
Type:
Grant
Filed:
March 24, 2000
Date of Patent:
April 2, 2002
Assignee:
BioWhittaker Molecular Applications, Inc.
Inventors:
Minjie Wu, Hugh W. White, Noriko Kusukawa, Thomas M. Stein
Abstract: The invention relates to a method for producing hydrophilic monomers which are particularly useful for electrophoresis and to electrophoresis compositions and coating compositions. The method uses the steps of reacting a (meth)acryloyl with an aminoalcohol in the presence of a base in a polar solvent, optionally filtering an aqueous solution of the reaction product, deionizing an aqueous solution of the reaction product, and removing the solvent.
Type:
Grant
Filed:
July 31, 1998
Date of Patent:
September 12, 2000
Assignee:
BioWhittaker Molecular Applications, Inc.