Abstract: An infant formula contains liposomes which improve the nutritional delivery of nutrients, stabilize ingredients, and enhance their bioavailabilty. The formula more closely resembles the ultrastructure and infrastructure of natural human milk due to the presence of liposomes. The lipid concentration is in the range of 0.1-50% of the formulation. The typical size of the liposomes range between about 20 nm and about 500 nm. The formula can be formulated to be in a liquid or dry form. The phospholipid concentration is the same as that which occurs in human milk.
Abstract: Certain diacylglycerol-polyethyleneglycol (DAG-PEG) lipids are especially useful for forming thermodynamically stable liposomes. Such liposomes are useful for a variety of purposes, including the delivery of therapeutic agents.
Abstract: A fast drying, spray-on cosmetic preparation containing pigments and texturants to simulate the appearance of wearing hosiery when applied to human skin. Specific tailoring of ranges of sizes for pigment and texturant particles simulates the color and texture appearance of hosiery in a durable, removable makeup that smoothes and moisturizes the skin.
Abstract: A lipid composition forms liposomes spontaneously upon mixing with an aqueous solution. The lipid composition includes diacylglycerol-PEG compounds. Such lipid compositions are useful for forming liposomes, which in turn are useful for a variety of purposes, including the delivery of therapeutic agents.
Type:
Grant
Filed:
July 8, 2005
Date of Patent:
December 19, 2006
Assignee:
BioZone Laboratories, Inc.
Inventors:
Brian Charles Keller, Alenka Lasic, legal representative, Dan D. Lasic, deceased
Abstract: The present invention comprises a group of related lipid molecules, and methods for their use, that maybe used to treat inflammation and certain inflammation related diseases. The group of related lipid molecules are capable of inhibiting certain enzyme systems including phospholipase A2, and cyclooxygenase-2. The group of related lipid molecules of the invention may be characterized by specific structural characteristics, or by specific biological activity, including inhibition of the previously listed enzymes.
Abstract: A liposome-capsule dosage unit system for the delivery of a biologically active material is formed by encapsulating a biologically active materials in liposomes and then placing the liposome encapsulated material into a capsule. The capsule is typically a soft gel capsule or a two piece capsule capable of tolerating a certain amount of water. A less water tolerant capsule can be employed if the liposomes are dehydrated prior to placement within the capsule. Biologically active material include drugs, nutritional supplements, vitamins, minerals, enzymes, hormones, proteins and polypeptides. The system is especially suited for the delivery of materials with poor oral solubility, materials that are not absorbed or are poorly absorbed from the gastrointestinal tract, and materials that have conventionally been given by an invasive route. The system can be administered orally, intra-occularly, intranasally, rectally, or vaginally.
Abstract: Substances, such as pharmaceuticals and cosmetics, are administered encapsulated within a lipid vesicle, by iontophoresis. An iontophoretic device which conforms to the contours of the body is also provided.
Type:
Grant
Filed:
July 22, 1996
Date of Patent:
April 11, 2000
Assignee:
BioZone Laboratories, Inc.
Inventors:
Brian C. Keller, Daniel L. Fisher, Stefan Kiss, Michael Mezei
Abstract: The present invention provides compositions and methods of administering nutritional supplements. The compositions and methods of the present invention are based on nutritional supplements that are encapsulated in lipid vesicles for administration as an aerosol or liquid droplet spray.
Type:
Grant
Filed:
May 14, 1996
Date of Patent:
April 6, 1999
Assignee:
BioZone Laboratories, Inc.
Inventors:
Brian C. Keller, Daniel L. Fisher, Steven Kiss