Abstract: The invention relates to elements for separating substances by distributing between a stationary and a mobile phase. Said separating elements comprise any stationary phase and a support element. The separating elements are part of a set that is provided with at least two separating elements Ti (i=2) encompassing different stationary phases Si (i=2). The set comprises at least three pieces of each type of separating element Ti with a specific stationary phase Si. The separating elements can be coupled to each other or interconnected in another manner so as to form a separating device. The invention further relates to a method for producing an optimized device for separating substance mixtures.