Abstract: The present disclosure relates compounds of Formula (I?): and pharmaceutically acceptable salts and stereoisomers thereof. The present disclosure also relates to methods of preparing the compounds, compositions comprising the compounds, and methods of using the compounds, e.g., in the treatment of cancer.
Abstract: The present disclosure relates compounds of Formula (I?): and pharmaceutically acceptable salts and stereoisomers thereof. The present disclosure also relates to methods of preparing the compounds, compositions comprising the compounds, and methods of using the compounds, e.g., in the treatment of cancer.
Type:
Application
Filed:
February 18, 2022
Publication date:
September 26, 2024
Applicant:
Black Diamond Therapeutics, Inc.
Inventors:
Pui Yee NG, Ivan JEWETT, Matthew C. LUCAS, Fernando PADILLA, Istvan J. ENYEDY
Abstract: The present disclosure relates to new compounds or pharmaceutically acceptable salts or stereoisomers thereof of formula I as inhibitors of receptor tyrosine kinases (RTK), in particular extracellular mutants of ErbB-receptors. The present disclosure also relates to methods of preparation these compounds, compositions comprising these compounds, and methods of using them in the treatment of cancer in mammals (e.g. humans).
Type:
Application
Filed:
March 12, 2021
Publication date:
November 17, 2022
Applicant:
Black Diamond Therapeutics, Inc.
Inventors:
Alexander FLOHR, Alexander MAYWEG, George TRAINOR, David M. EPSTEIN, Matthew O'CONNOR, Elizabeth BUCK, Luca ARISTA
Abstract: The present disclosure relates to new compounds or pharmaceutically acceptable salts or stereoisomers thereof of formula I as inhibitors of receptor tyrosine kinases (RTK), in particular extracellular mutants of ErbB-receptors. The present disclosure also relates to methods of preparation these compounds, compositions comprising these compounds, and methods of using them in the treatment of cancer in mammals (e.g. humans).
Type:
Grant
Filed:
April 17, 2020
Date of Patent:
June 15, 2021
Assignee:
Black Diamond Therapeutics, Inc.
Inventors:
Alexander Flohr, Alexander Mayweg, George Trainor, David M. Epstein, Matthew O'Connor, Elizabeth Buck, Luca Arista