Patents Assigned to BlinkBio, Inc.
  • Silanol based therapeutic payloads
    Patent number: 11497757
    Abstract: Described herein in part are silanol based therapeutic payloads comprising a silanol terminus, a divalent spacer moiety, and a drug moiety capable of effecting a target cell or tissue.
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: November 15, 2022
    Assignee: BlinkBio, Inc.
    Inventors: Hanh N. Nguyen, Leslie O. Ofori, Jutta Wanner, Douglas S. Werner
  • Silicon based drug conjugates and methods of using same
    Patent number: 11291731
    Abstract: Described herein are silicon based conjugates capable of delivering one or more payload moieties to a target cell or tissue. Contemplated conjugates may include a silicon-heteroatom core, one or more optional catalytic moieties, a targeting moiety that permits accumulation of the conjugate within a target cell or tissue, one or more payload moieties (e.g., a therapeutic agent or imaging agent), and two or more non-interfering moieties covalently bound to the silicon-heteroatom core.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: April 5, 2022
    Assignee: BlinkBio, Inc.
    Inventors: Kenneth W. Foreman, Hanh N. Nguyen, Leslie O. Ofori, Jutta Wanner, Douglas S. Werner
  • Silanol based therapeutic payloads
    Patent number: 10716801
    Abstract: Described herein in part are silanol based therapeutic payloads comprising a silanol terminus, a divalent spacer moiety, and a drug moiety capable of effecting a target cell or tissue.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: July 21, 2020
    Assignee: BlinkBio, Inc.
    Inventors: Hanh Nho Nguyen, Leslie Odame Ofori, Jutta Wanner, Douglas S. Werner
  • Silanol based therapeutic payloads
    Patent number: 10293053
    Abstract: Described herein in part are silanol based therapeutic payloads comprising a silanol terminus, a divalent spacer moiety, and a drug moiety capable of effecting a target cell or tissue.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: May 21, 2019
    Assignee: BlinkBio, Inc.
    Inventors: Hanh N. Nguyen, Leslie O. Ofori, Jutta Wanner, Douglas S. Werner
  • Silanol Based Therapeutic Payloads
    Publication number: 20190111142
    Abstract: Described herein in part are silanol based therapeutic payloads comprising a silanol terminus, a divalent spacer moiety, and a drug moiety capable of effecting a target cell or tissue.
    Type: Application
    Filed: December 18, 2018
    Publication date: April 18, 2019
    Applicants: BlinkBio, Inc., BlinkBio, Inc.
    Inventors: Hanh N. Nguyen, Leslie O. Ofori, Jutta Wanner, Douglas S. Werner
  • Silanol based therapeutic payloads
    Patent number: 10064880
    Abstract: Described herein in part are silanol based therapeutic payloads comprising a silanol terminus, a divalent spacer moiety, and a drug moiety capable of effecting a target cell or tissue.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: September 4, 2018
    Assignee: BlinkBio, Inc.
    Inventors: Hanh N. Nguyen, Leslie O. Ofori, Jutta Wanner, Douglas S. Werner
  • Silicon based drug conjugates and methods of using same
    Patent number: 9931407
    Abstract: Described herein are silicon based conjugates capable of delivering one or more payload moieties to a target cell or tissue. Contemplated conjugates may include a silicon-heteroatom core, one or more optional catalytic moieties, a targeting moiety that permits accumulation of the conjugate within a target cell or tissue, one or more payload moieties (e.g., a therapeutic agent or imaging agent), and two or more non-interfering moieties covalently bound to the silicon-heteroatom core.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: April 3, 2018
    Assignee: BlinkBio, Inc.
    Inventors: Kenneth W. Foreman, Hanh N. Nguyen, Leslie O. Ofori, Jutta Wanner, Douglas S. Werner
  • Coferons and methods of making and using them
    Patent number: 9771345
    Abstract: The present invention is directed to a monomer useful in preparing therapeutic compounds. The monomer includes one or more pharmacophores which potentially binds to a target molecule with a dissociation constant of less than 300 ?M and a linker element connected to the pharmacophore. The linker element has a molecular weight less than 500 daltons, is connected, directly or indirectly through a connector, to the pharmacophore.
    Type: Grant
    Filed: October 7, 2010
    Date of Patent: September 26, 2017
    Assignees: Cornell University, Purdue Research Foundation, BlinkBio, Inc.
    Inventors: Francis Barany, Maneesh Pingle, Sarah Filippa Giardina, Donald Bergstrom, Lee Daniel Arnold