Abstract: The invention provides a method and system for operating multiple communicating caches. Between caches, unnecessary transmission of repeated information is substantially reduced. Each cache maintains information to improve the collective operation of the system of multiple communicating caches. This can include information about the likely contents of each other cache, or about the behavior of client devices or server devices coupled to other caches in the system. Pairs of communicating caches substantially compress transmitted information. This includes both reliable compression, in which the receiving cache can reliably identify the compressed information in response to the message, and unreliable compression, in which the receiving cache will sometimes be unable to identify the compressed information. A first cache refrains from unnecessarily transmitting the same information to a second cache when each already has a copy.