Abstract: A system for enhanced sealing of coupled medical lines includes a male fitting, a female fitting, and a flexible annular collar seal. The seal provides a sealing function to an open end of the connector. The male fitting is made of medical grade materials and includes a male connector fluidly coupled to a first line. The female fitting is made of medical grade materials and including a female connector fluidly coupled to a second line and configured to mate with the male connector. The seal is made of a medical grade polymer coupled to one or both the male fitting and the female fitting.

Abstract: A system for enhanced sealing of coupled medical fluid or vascular access lines includes a male fitting, a female fitting, and an annular collar seal which is affixable to the male fitting. After the annular collar seal is affixed to the male fitting, the female fitting is placed through the collar and connected to the male fitting.