Abstract: A device for indicating violation of a temperature limit of an item is provided. The device is positionable near the item and includes a sensor configured to change its state permanently when the temperature limit is violated. The change in sensor state is machine-readable to provide a permanent indication of the temperature limit violation. The sensor includes a reservoir for storing a fluid that changes phase from a solid to a liquid when the temperature limit is violated and a channel in fluid communication with the reservoir for receiving flow of the fluid in liquid phase from the reservoir. The sensor is arranged to allow flow of the fluid in the liquid phase such that the state of the sensor is permanently changed. The sensor is further configured to prevent the fluid flow from permanently changing the sensor state until activation of the sensor from a resting state. A system and method for detecting violation of a temperature limit of an item using the device is also provided.

Abstract: A method of maintaining a thermal history (369; 699) of samples stored in a temperature-controlled sample storage system is provided. The system can include: one or more containers (218, 220; 522) each storing one of the samples; one or more storage objects (210-216, 208; 510, 516-518, 520; 654-660, 662) each housing one or more containers or other storage objects; one or more structures (200-206; 512; 650) defining a temperature-controlled storage environment and housing the one or more storage objects; machine readable tags (14) each of which is associated with a separate container and storage object, each tag encoding an identification code and having a temperature-dependant characteristic; and an interrogator (12) for reading the identification code and the temperature-dependant characteristic.

Abstract: A method of tagging and sterilizing an item, the method including the steps of: providing an item (12) that is to be sterilized and tagged; applying an RFID tagging device (22) to said item, said tagging device including a data store (30) formed from an array of micromechanical resonant members (34), said resonant members being configured to vibrate in accordance with an applied RF signal, so as to provide a data response; and sterilizing said tagged item by autoclaving and/or by irradiation.