Abstract: Provided are methods and systems for metagenomic analysis. Methods involve generating libraries and databases of taxonomic signatures informative of taxonomic information in a heterogeneous microbial sample. Methods also include identification of microorganisms and biochemical activities in the sample, including identification at a plurality of taxonomic levels.
Type:
Grant
Filed:
March 1, 2018
Date of Patent:
September 24, 2024
Assignees:
BLUEDOT, LLC, TRIAD NATIONAL SECURITY, LLC
Inventors:
Momchilo Vuyisich, Jason Gans, Niels Klitgord, Po-E Li, Patrick Chain
Abstract: Provided herein are compositions and methods for analyzing nucleic acids in a sample. Compositions include simple barcode sets having reduced DNA sequencing instrument-specific error rates. Methods include methods to deconvolute sequence reads from different samples.
Type:
Grant
Filed:
June 21, 2018
Date of Patent:
July 16, 2024
Assignees:
BLUEDOT, LLC, TRIAD NATIONAL SECURITY, LLC
Inventors:
Momchilo Vuyisich, Jason Gans, Patrick Chain, Andrew Hatch