Abstract: A method is provided for operating a system for the liquefaction of gas of the type comprising a main heat exchange vessel, a bundle for the gas to be liquefied extending through said MCHE and a refrigerant compression circuit of which a first end leads evaporated refrigerant from the vessel towards a compressor and a second end supplies the compressed and cooled refrigerant from the compressor towards the MCHE. For avoiding problems during heat up or during start up of the heat exchanger the pressure within the liquefaction system is controlled by regulating the amount of evaporated refrigerant in the liquefaction circuit.