Abstract: The present invention relates to methods for inducing a broadly reactive immune response to multiple strains of influenza in a subject comprising intranasally administering a nanoemulsion vaccine composition comprising a computationally optimized influenza immunogen or protein.
Type:
Application
Filed:
April 11, 2023
Publication date:
February 22, 2024
Applicant:
BlueWillow Biologics, Inc.
Inventors:
Shyamala Ganeson, Vira Bitko, Ali Fattom
Abstract: The present disclosure relates to compositions and methods for inducing an immune response to a composition of the invention in a subject. Additionally, the present disclosure generally relates to methods for screening for immune response to a composition of the invention.
Type:
Grant
Filed:
June 19, 2018
Date of Patent:
May 9, 2023
Assignees:
Washington University, BLUEWILLOW BIOLOGICS
Inventors:
Shabaana Abdul Khader, Mushtaq Ahmed, Ali Fattom, Douglas Smith, Tarek Hamouda
Abstract: The present disclosure relates to nanoemulsion compositions with certain surfactant blend ratios that impart enhanced permeability. Such compositions are useful for topical, mucosal and intranasal applications and allow for the greater delivery of one or more active agents to the application site to prevent infection by a microorganism.
Abstract: The present application relates to the field of human immunology, in particular, a herpes simplex virus (HSV) vaccine. The subunit vaccine composition comprises isolated surface glycoproteins from herpes simplex viruses, fusion proteins or fragments thereof mixed in varied combination with a nanoemulsion, which is a potent immune enhancer.
Type:
Application
Filed:
October 18, 2021
Publication date:
April 7, 2022
Applicant:
BlueWillow Biologics, Inc.
Inventors:
Ali I. Fattom, Jakub Simon, James R. Baker, JR., Tarek Hamouda, Vira Bitko
Abstract: The present disclosure relates to nanoemulsion compositions with certain surfactant blend ratios that impart enhanced permeability. Such compositions are useful for topical, mucosal, vaginal, and intranasal applications and allow for the greater delivery of one or more active agents to the application site.
Abstract: The present disclosure relates to nanoemulsion vaccine compositions and methods of making and using the same. The disclosed compositions and methods provide a means of treating, preventing, or protecting an individual from anthrax exposure or poisoning.
Abstract: The present application relates to the field of human immunology, in particular, a herpes simplex virus (HSV) vaccine. The subunit vaccine composition comprises isolated surface glycoproteins from herpes simplex viruses, fusion proteins or fragments thereof mixed in varied combination with a nanoemulsion, which is a potent immune enhancer.
Type:
Grant
Filed:
November 15, 2018
Date of Patent:
October 19, 2021
Assignee:
BlueWillow Biologics, Inc.
Inventors:
Ali I. Fattom, Jakub Simon, James R. Baker, Jr., Tarek Hamouda, Vira Bitko
Abstract: The present disclosure relates to nanoemulsion compositions with certain surfactant blend ratios that impart enhanced permeability. Such compositions are useful for topical, mucosal and intranasal applications and allow for the greater delivery of one or more active agents to the application site to prevent infection by a microorganism.
Abstract: The present disclosure relates to nanoemulsion compositions with certain surfactant blend ratios that impart enhanced permeability. Such compositions are useful for mucosal and intranasal applications and allow for the greater delivery of one or more active agents to the application site to prevent infection by coronavirus.