Patents Assigned to Board of Regents
  • Patent number: 12365761
    Abstract: The present disclosure relates to degradable polymers which contain a hydrophobic and hydrophilic segment which is sensitive to pH. In some aspects, the polymers form a micelle which is sensitive to pH and have backbones which are capable of undergoing degradation in vivo. In some aspects, the disclosure also provides methods of using these degradable polymers for the delivery of a drug.
    Type: Grant
    Filed: June 22, 2020
    Date of Patent: July 22, 2025
    Assignee: The Board of Regents of The University of Texas System
    Inventors: Jinming Gao, Xu Wang, Houliang Tang, Wei Li, Jonathan Wilhelm, Baran Sumer
  • Patent number: 12364395
    Abstract: A system for calculating a Grüneisen parameter of a target tissue is disclosed. The system comprises a first light source configured to emit a first light signal to the target tissue, thereby generating an acoustic signal in the target tissue. The system further comprises a second light source configured to emit a second light signal to the target tissue, which interacts with the acoustic signal, (e.g., in the manner of Brillouin scattering) to generate a backscattered light signal. The system further comprise a light sensor configured to detect the backscattered light signal and a processor configured to receive the backscattered light signal from the light sensor and calculate the Grüneisen parameter of the target tissue based on the backscattered response signal.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: July 22, 2025
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Barbara Smith, Christopher Miranda
  • Publication number: 20250233550
    Abstract: Clamping systems including a clamp configured to clamp a photovoltaic panel flange to a base bracket flange are generally described. In some embodiments, the clamp may include two or more sets of legs connected to each other, each set of legs extending from an apex joint, with each leg including a receiving slot for receiving the panel flange and bracket flange therein. In some embodiments, the clamp includes teeth configured to interlock with grooves formed on the bracket flange.
    Type: Application
    Filed: January 10, 2025
    Publication date: July 17, 2025
    Applicant: The Board of Regents of the University of Oklahoma
    Inventor: Andres F. Cavieres Pinilla
  • Publication number: 20250228788
    Abstract: The present disclosure provides compositions which shown preferential targeting or delivery of a nucleic acid composition to a particular organ. In some embodiments, the composition comprises a steroid or sterol, an ionizable cationic lipid, a phospholipid, a PEG lipid, and a permanently cationic lipid which may be used to deliver a nucleic acid.
    Type: Application
    Filed: January 16, 2025
    Publication date: July 17, 2025
    Applicant: The Board of Regents of The University of Texas System
    Inventors: Qiang CHENG, Tuo WEI, Daniel J. SIEGWART
  • Publication number: 20250229336
    Abstract: A time-based prediction model that models surface roughness of an additively manufactured (AM) component as a single equivalent notch with a crack at the notch root in which the notch reflects the stress concentration due to an entire spectrum of surface roughness of the AM component is disclosed herein.
    Type: Application
    Filed: January 7, 2025
    Publication date: July 17, 2025
    Applicant: Arizona Board of Regents on Behalf of Arizona State University
    Inventor: Yongming Liu
  • Patent number: 12362529
    Abstract: A solid-state laser system includes a gain medium having an optical resonator defined therein. The gain medium is co-doped with first and second active elements. The first active element is Er3+ and the second active element is Ho3+ or Dy3+. The solid-state laser system also includes a pump source coupled to the gain medium for pumping the gain medium with pump light.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: July 15, 2025
    Assignee: Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Xiushan Zhu, Nasser N. Peyghambarian
  • Patent number: 12359266
    Abstract: The present invention includes a method and kit for single-primer tiled sequencing comprising: reverse transcribing a target nucleic acid with multiple tiled primers spaced along the genome, each only targeting one annealing site to form amplicons in the presence of terminating 3? azido nucleotides to incorporate the terminating 3? azido nucleotides into the cDNA; click-ligating a downstream primer onto tire 3? azido terminated cDNA such that a second template-specific primer is not required; amplifying the click-ligated cDNA; and sequencing the amplicons.
    Type: Grant
    Filed: June 18, 2021
    Date of Patent: July 15, 2025
    Assignee: Board of Regents, The University of Texas System
    Inventors: Andrew Routh, Elizabeth Jaworski
  • Patent number: 12359340
    Abstract: The invention relates in part to a growth model for the growth of Group III-Group V (III-V) alloys by molecular beam epitaxy (MBE) based on the kinetics of adsorption, desorption, incorporation, anion exchange, anion-assisted removal, and surface droplet accumulation of the Group V elements. The invention also relates to methods to optimize MBE growth conditions used to produce a target III-V alloy composition. The invention is further related to methods of predicting III-V alloy compositions resulting from a set of MBE growth conditions.
    Type: Grant
    Filed: December 16, 2021
    Date of Patent: July 15, 2025
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Stephen T. Schaefer, Marko S. Milosavljevic, Rajeev Reddy Kosireddy, Shane R. Johnson
  • Patent number: 12357682
    Abstract: The invention generally relates to the development of immunogenic compositions comprising a DNA copy of at least one live attenuated plus-sense single-stranded RNA virus genome, such as the genome of a live-attenuated Zika vims (ZIKV), Japanese encephalitis virus (JEV) or yellow fever vims (YFV). The immunogenic compositions can be used for treating or conferring protective immunity against diseases related to plus-sense single-stranded RNA viruses, e.g. for affording prolonged immunoprotection against such viruses and protective immunity is conferred at low diseases, e.g., as low as 300 or 500 ng after administration of a single pLAV dosage.
    Type: Grant
    Filed: August 30, 2019
    Date of Patent: July 15, 2025
    Assignee: Board of Regents, The University of Texas System
    Inventors: Jing Zou, Xuping Xie, Pei-Yong Shi
  • Publication number: 20250226119
    Abstract: Disclosed are techniques for initiating and sustaining a transport barrier within a magnetically confined plasma in a plasma fusion device. For a toroidal magnetic configuration, a characteristic region of the magnetic field can be established by generating a current within the plasma or by other means. The location of the characteristic region can be controlled to be suitably close to the interior walls of the plasma fusion device to allow a quantity of particles to be injected into the plasma at or inside the characteristic region. The quantity of particles can augment the density of the plasma and create a density gradient within the characteristic region, resulting in the formation of a transport barrier at or inside the characteristic region.
    Type: Application
    Filed: March 31, 2023
    Publication date: July 10, 2025
    Applicant: Board of Regents, The University of Texas System
    Inventors: Michael Thomas Kotschenreuther, Swadesh Mahajan, David R. Hatch, Xing Liu, Gabriele Merlo
  • Patent number: 12350672
    Abstract: Described herein are systems relating to a continuous-flow instrument that includes all necessary components for digital droplet quantification without the need to introduce key reagents or collect and transfer droplets between stages of instrument operation. Digital quantification can proceed without any additional fluid or consumable handling and without exposing fluids to risk of external contamination.
    Type: Grant
    Filed: March 6, 2024
    Date of Patent: July 8, 2025
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Cody Youngbull, Andrew Hatch, Andrew Larsen, Tathagata Ray, Matthew Underhill
  • Patent number: 12351877
    Abstract: The present disclosure relates to methods of determining a treatment course of action. In particular, the present disclosure relates to compositions and methods for determining responsiveness to estrogen and estrogen blocking therapies for cancer.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: July 8, 2025
    Assignee: Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Ghassan Mouneimne, Marco Padilla-Rodriguez
  • Patent number: 12355526
    Abstract: Multi-stage distributed beamforming for distributed mosaic wireless networks is provided. Embodiments described herein present systems, devices, and methods that provide increased range, data rate, and robustness to interference and jamming. A distributed mosaic wireless network includes a transmitter, a receiver, and one or more distributed clusters of radios referred to herein as mosaics or relay mosaics. Each mosaic consists of several distributed, cooperative radio transceivers (e.g., mosaic nodes) that relay a signal sent by the transmitter towards the receiver. In some embodiments, a single-stage beamforming technique is implemented whereby the transmitter sends a signal to a first mosaic, which then relays this signal by beamforming to the receiver. In some embodiments, a multi-stage beamforming technique is implemented whereby the transmitter sends a signal to a first mosaic, which then relays this signal by beamforming to a second mosaic, which then relays this signal by beamforming to the receiver.
    Type: Grant
    Filed: February 2, 2024
    Date of Patent: July 8, 2025
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Andrew Herschfelt, Jacob Holtom, Owen Ma, Daniel W. Bliss
  • Patent number: 12352952
    Abstract: A design and implementation of a new optical architecture: space, time, and angular division multiplexed image transfer by Digital Micromirror Device. The method, like various multiplexing methods employed in communication engineering, enables image transfer via an angular band-limited data channel such as an optical image guide by dynamically redistributing a signal into multiple domains such as space, time, angle, wavelength, and polarization.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: July 8, 2025
    Assignee: Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Yuzuru Takashima, Brandon Hellman
  • Publication number: 20250216648
    Abstract: A heliostat includes a reflector that has at least one segment arranged in a segment assembly and that defines a reflecting surface; a rigid spaceframe structure that includes a plurality of struts joined at nodes, the plurality of struts supporting the segment assembly so as to hold the reflecting surface in a concave toroidal shape; a dual-axis mount constructed and arranged to support and orient the rigid spaceframe structure and the segment assembly so as to reflect sunlight incident on the reflecting surface toward a distant receiving surface, the dual-axis mount including at least two drives; at least one mechanical linkage coupled to at least one drive of the dual-axis mount and configured to change a relative position of at least two nodes of the rigid spaceframe structure in synchronization with motion of the at least one drive, and thereby changing a shape of the rigid spaceframe structure and the reflector.
    Type: Application
    Filed: March 20, 2023
    Publication date: July 3, 2025
    Applicant: Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: James Roger P. ANGEL, Nicholas DIDATO, Matthew L. RADEMACHER
  • Publication number: 20250215019
    Abstract: Disclosed herein are methods of synthesizing compounds of the formula wherein the variables are defined herein. Also provided are compounds produced using these methods. In some aspects, the methods provided herein may be used to create di- and tri-substituted BCPs.
    Type: Application
    Filed: March 17, 2023
    Publication date: July 3, 2025
    Applicant: The Board of Regents of The University of Texas System
    Inventors: Yangyang YANG, Jet TSIEN, Tian QIN
  • Patent number: 12343674
    Abstract: A system and method for passive collection of atmospheric carbon dioxide is disclosed. The system includes a harvest chamber having a first opening and a sorbent regeneration system. The system also includes a capture body coupled to and movable by a support structure. The capture body includes a sorbent material and is movable by the support structure to be in a collection configuration wherein at least a portion of the capture body is in contact with a natural airflow outside the harvest chamber such that atmospheric carbon dioxide is captured by the sorbent material, and a release configuration wherein at least a portion of the capture body holding captured carbon dioxide is operated upon by the regeneration system inside the harvest chamber such that captured carbon dioxide is released to form an enriched gas.
    Type: Grant
    Filed: July 10, 2023
    Date of Patent: July 1, 2025
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Klaus Lackner, Shreyans Kedia, Brinton Carlson, Robert Page, Venkatram Choodamani, Allen Wright
  • Patent number: 12345446
    Abstract: A system for providing a contour map of the surface of a heliostat from reflected sunlight using a fly's eye camera. The system includes an entrance screen configured to receive sunlight reflected by said heliostat; an array of imaging apertures extending across the entrance screen, each aperture forming an image of said heliostat from a different viewpoint to provide a plurality of heliostat images; one or more digital cameras configured to view all of said plurality of heliostat images; an image processor configured to map out from the plurality of heliostat images a location of sunlight delivered to the entrance screen to obtain a plurality of maps, and to provide, based on centroids of said maps a tip and tilt of each said subsection The reflecting surface profile of the heliostat is obtained by integration of the subsection tilts across all the subsections.
    Type: Grant
    Filed: March 8, 2022
    Date of Patent: July 1, 2025
    Assignee: Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Ryker Eads, James Roger P. Angel
  • Patent number: 12336976
    Abstract: Disclosed herein are methods of treating a tumor or cancer in a subject whose tumor or cancer cells express low levels of asparagine synthetase (ASNS), and compounds and compositions useful in such treatment. Also disclosed herein are methods of evaluating whether to administer a compound that inhibits glutathione production or a glutaminase inhibitor to a subject with a tumor or cancer.
    Type: Grant
    Filed: September 6, 2023
    Date of Patent: June 24, 2025
    Assignee: Board of Regents, The University of Texas System
    Inventors: Timothy Heffernan, Jeffrey Kovacs, Nakia Spencer, Christopher Bristow
  • Patent number: 12336982
    Abstract: Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: June 24, 2025
    Assignees: Rodeo Therapeutics Corporation, Case Western Reserve University, Board of Regents of the University of Texas System
    Inventors: Sanford Markowitz, Joseph Ready, Stephen L. Gwaltney, II, Monika Antczak