Abstract: A polymer suitable for use in affinity chromatography comprising a polymer f an aminimide and a vinyl compound having at least one pendant halo-methyl group and the said polymer wherein an amine ligand which affords sites for binding in affinity chromatography is coupled to the polymer by reaction with a portion of the pendant halo-methyl groups and the remainder of said pendant halo-methyl groups are reacted with an amine containing a pendant hydrophilic group. The invention also comprises a method of coating a substrate with the above polymer and a method of fractionating mixtures by affinity chromatography employing the above polymer as an adsorbent.
Type:
Grant
Filed:
November 16, 1977
Date of Patent:
April 7, 1981
Assignee:
Board of Regents, for and on behalf of the University of Florida
Abstract: Compositions possessing a porous, high specific area, silica-rich surface, or capable of developing such a surface in vivo, form strong bonds with bone tissue. These compositions are thus excellent materials for dental and surgical implants, or the coatings thereof. Examples of such compositions include highly porous glasses and glass-ceramics comprising at least about 80 weight percent silicon dioxide, hardened inorganic cements such as Portland cement and known silicon dioxide-based biologically active glasses and glass-ceramics. Neither calcium, sodium nor phoshorus compounds are necessary ingredients. Cements which develop the above described surface characteristics in vivo form a strong bond with both bone and implant when used in the fixation of dental and surgical implants, especially those made or coated with a biologically active silicon dioxide-based glass or glass-ceramic.
Type:
Grant
Filed:
April 5, 1978
Date of Patent:
October 23, 1979
Assignee:
Board of Regents, for and on behalf of the University of Florida
Abstract: A polymer suitable for use in affinity chromatography comprising a polymer f an aminimide and a vinyl compound having at least one pendant halo-methyl group and the said polymer wherein an amine ligand which affords sites for binding in affinity chromatography is coupled to the polymer by reaction with a portion of the pendant halo-methyl groups and the remainder of said pendant halo-methyl groups are reacted with an amine containing a pendant hydrophilic group.The invention also comprises a method of coating a substrate with the above polymer and a method of fractionating mixtures by affinity chromatography employing the above polymer as an adsorbent.
Type:
Grant
Filed:
June 30, 1976
Date of Patent:
July 24, 1979
Assignee:
Board of Regents, for and on behalf of the University of Florida