Patents Assigned to Board of Regents of the University of Okla.
  • Streptokinase-coding recombinant vectors
    Patent number: 5066589
    Abstract: A recombinant vector adapted for transformation of a suitable microorganism host to produce and secrete streptokinase. The recombinant vector comprises a plasmid into which a polydeoxyribonucleotide fragment from Streptococcus equisimilis H46A which codes for streptokinase synthesis and secretion has been inserted. The transformant microorganism including this recombinant plasmid vector produces streptokinase suitable for clinical fibrinolytic usage after purification.
    Type: Grant
    Filed: June 27, 1988
    Date of Patent: November 19, 1991
    Assignee: Board of Regents of the University of Okla.
    Inventors: Joseph J. Ferretti, Horst Malke