Abstract: Disclosed are various defined combinations of agents for use in improved anti-vascular therapies and coagulative tumor treatment. Particularly provided are combined treatment methods, and associated compositions, pharmaceuticals, medicaments, kits and uses, which together function surprisingly effectively in the treatment of vascularized tumors. The invention preferably involves a component or treatment step that enhances the effectiveness of therapy using targeted or non-targeted coagulants to cause tumor vasculature thrombosis.
Type:
Application
Filed:
September 27, 2002
Publication date:
July 24, 2003
Applicant:
Board of Regents, The University of Texas System and Peregrine Pharmaceuticals, Inc.
Inventors:
Philip E. Thorpe, Steven W. King, Claudia Gottstein
Abstract: Disclosed are various defined combinations of agents for use in improved anti-vascular therapies and coagulative tumor treatment. Particularly provided are combined treatment methods, and associated compositions, pharmaceuticals, medicaments, kits and uses, which together function surprisingly effectively in the treatment of vascularized tumors. The invention preferably involves a component or treatment step that enhances the effectiveness of therapy using targeted or non-targeted coagulants to cause tumor vasculature thrombosis.
Type:
Application
Filed:
September 27, 2002
Publication date:
July 10, 2003
Applicant:
Board of Regents, The University of Texas System and Peregrine Pharmaceuticals, Inc.
Inventors:
Philip E. Thorpe, Steven W. King, Claudia Gottstein