Patents Assigned to Board of Regents, The University Of Texus System
  • Method of use of cardiotonic drugs and inhibitors of nitric oxide synthesis to alleviate pathologic hypotension
    Patent number: 5776979
    Abstract: The present invention involves a method for prophylaxis or treatment of an animal for systemic hypotension induced by endotoxin and/or a biological response modifier such as the cytokines, IFN, TNF, IL-1 or IL-2 and the like. The method involves administering, preferably intravascularly, a therapeutically effective amount of dobutamine and an inhibitor of nitric oxide formation from arginine.
    Type: Grant
    Filed: March 31, 1995
    Date of Patent: July 7, 1998
    Assignees: Board of Regents, The University Of Texus System, Cornell Research Foundation, Inc.
    Inventors: Robert G. Kilbourn, Steven S. Gross, Owen W. Griffith