Patents Assigned to Board of Regents, The University of
  • Analytical technique for measuring bound glycerides in a biodiesel composition
    Patent number: 8476075
    Abstract: A method of estimating the amount of unreacted starting materials (glycerides, methyl esters, etc.) and the composition of a biodiesel using TLC in conjunction with a lipophilic dye, Nile Red is described herein. The dye based TLC method of the present invention is convenient and provides significant advantages over existing methods for estimating the purity of a biodiesel composition.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: July 2, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventors: Eva Deemer, Wen Yee Lee, Xiomara Carolina Chianelli
  • ANTIMICROBIAL FLUSH SOLUTIONS
    Publication number: 20130164363
    Abstract: The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including surfaces of indwelling medical devices and organic surfaces such as skin and sutures, and inorganic surfaces such as hospital equipment, pipelines etc.
    Type: Application
    Filed: September 17, 2012
    Publication date: June 27, 2013
    Applicant: Board of Regents, The University of Texas System
    Inventor: Issam RAAD
  • Methods and compositions for targeting macromolecules into the nucleus
    Patent number: 8470976
    Abstract: The present invention includes compositions, methods and kits for directing an agent across the nuclear membrane of a cell. The present invention includes a Karyopherin beta2 translocation motif in a polypeptide having a slightly positively charged region or a slightly hydrophobic region and one or more R/K/H-X(2-5)-P-Y motifs. The polypeptide targets the agent into the cell nucleus.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: June 25, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventor: Yuh Min Chook
  • Graphene synthesis by chemical vapor deposition
    Patent number: 8470400
    Abstract: Processes for synthesizing graphene films. Graphene films may be synthesized by heating a metal or a dielectric on a substrate to a temperature between 400° C. and 1,400° C. The metal or dielectric is exposed to an organic compound thereby growing graphene from the organic compound on the metal or dielectric. The metal or dielectric is later cooled to room temperature. As a result of the above process, standalone graphene films may be synthesized with properties equivalent to exfoliated graphene from natural graphite that is scalable to size far greater than that available on silicon carbide, single crystal silicon substrates or from natural graphite.
    Type: Grant
    Filed: May 5, 2010
    Date of Patent: June 25, 2013
    Assignees: Board of Regents, The University of Texas System, Texas Instruments, Inc.
    Inventors: Luigi Colombo, Xuesong Li, Rodney S. Ruoff
  • Di-functional surfactants for enhanced oil recovery
    Patent number: 8459360
    Abstract: The present invention describes the synthesis and use of cleavable di-functional anionic surfactants for enhanced oil recovery applications and/or the use of sacrificial surfactants.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: June 11, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventors: Gary A. Pope, Upali P. Weerasooriya, Quoc P. Nguyen, Larry N. Britton
  • Synthesizing graphene from metal-carbon solutions using ion implantation
    Patent number: 8461028
    Abstract: A method and semiconductor device for synthesizing graphene using ion implantation of carbon. Carbon is implanted in a metal using ion implantation. After the carbon is distributed in the metal, the metal is annealed and cooled in order to precipitate the carbon from the metal to form a layer of graphene on the surface of the metal. The metal/graphene surface is then transferred to a dielectric layer in such a manner that the graphene layer is placed on top of the dielectric layer. The metal layer is then removed. Alternatively, recessed regions are patterned and etched in a dielectric layer located on a substrate. Metal is later formed in these recessed regions. Carbon is then implanted into the metal using ion implantation. The metal may then be annealed and cooled in order to precipitate the carbon from the metal to form a layer of graphene on the metal's surface.
    Type: Grant
    Filed: October 8, 2012
    Date of Patent: June 11, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventors: Luigi Colombo, Robert M. Wallace, Rodney S. Ruoff
  • Methods and Compositions for Chlamydial Antigens as Reagents for Diagnosis of Tubal Factor Infertility and Chlamydial Infection
    Publication number: 20130143757
    Abstract: The present invention provides Chlamydia proteins and fragments thereof and methods of use in diagnostic assays.
    Type: Application
    Filed: November 30, 2012
    Publication date: June 6, 2013
    Applicant: Board of Regents, The University of Texas System
    Inventor: Guangming Zhong
  • Influenza A virus vaccines and inhibitors
    Patent number: 8455621
    Abstract: The present invention includes compositions and methods related to the structure and function of the cellular polyadenylation and specificity factor 30 (CPSF30) binding site on the surface of the influenza A non-structural protein 1 (NS1). Specifically, critical biochemical reagents, conditions for crystallization and NMR analysis, assays, and general processes are described for (i) discovering, designing, and optimizing small molecule inhibitors of influenza A (avian flu) viruses and (ii) creating attenuated influenza virus strains suitable for avian and human flu vaccine development.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: June 4, 2013
    Assignees: Rutgers, The State University of New Jersery, Board of Regents, The University of Texas System
    Inventors: Robert M. Krug, Karen Y. Twu, Rei-Lin Kuo, Gaetano Montelione, Edward Arnold, Kalyan Das, LiChung Ma, Rong Xiao
  • System and method for solving multiobjective optimization problems
    Patent number: 8458104
    Abstract: A system and method for solving a set of optimization problems initializes a current region of solutions for the set of optimization problems, performs a reduction phase, and provides the optimal solutions within the current region. The reduction phase creates a random sample of points within the current region and identifies a subregion of the current region that very likely does not contain any optimal solutions. The identified subregion is then removed from the current region. If the current region does not satisfies one or more convergence criteria, the process loops back to create another random sample of points and repeats the above-described steps. If, however, the current region does satisfy the convergence criteria, the optimal solutions within the current region are provided to the output device.
    Type: Grant
    Filed: June 17, 2010
    Date of Patent: June 4, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventor: Klaus Truemper
  • Magneto-motive ultrasound detection of magnetic nanoparticles
    Patent number: 8454511
    Abstract: Provided herein are systems, methods and compositions for the use of ultrasound for detection of cells and nanoparticles.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: June 4, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventors: Thomas E. Milner, Marc D. Feldman, Christopher Condit, Jung-Hwan Oh
  • Fluid Based RC Filter for Tuning Cut-Off Frequency and for Analytical Detection
    Publication number: 20130138359
    Abstract: An RC filter that is tunable in terms of its cut-off frequency comprising a drop placed on one or more dielectric layers, a conducting layer underneath the dielectric layer, a nonconducting layer underneath the conducting layer, and an external resistor attached to the drop via an electrode, wherein the cut-off frequency of the filter is tuned by changing the shape or composition of the drop and methods of using the filter as a detector.
    Type: Application
    Filed: August 19, 2011
    Publication date: May 30, 2013
    Applicant: Board of Regents, The University of Texas System
    Inventors: Daniel W. Armstrong, Yasith S. Nanayakkara, Hyejin Moon
  • MUC18 targeting peptides
    Patent number: 8450278
    Abstract: Provided are MUC 18 targeting peptides which may be used, e.g., to therapeutically target B-I lymphocytes to reduce the influence of these cells on the metastatic potential of melanoma cells and/or to target cancerous cells, including certain melanoma and leukemia cells. MUC 18 targeting peptides may be comprised in fusion constructs, imaging constructs, and/or therapeutic constructs such as fusion constructs which may be used for diagnosing or treating a cancer.
    Type: Grant
    Filed: October 15, 2009
    Date of Patent: May 28, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventors: Fernanda Staquicini, Renata Pasqualini, Wadih Arap
  • Efficient synthesis of galanthamine
    Patent number: 8450365
    Abstract: The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine related derivatives and intermediates thereof. In further embodiments, the invention relates to methods for improving the efficiency and overall yield of galanthamine and intermediates thereof.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: May 28, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventors: Philip D. Magnus, Ben Fauber, Neeraj Sane
  • METHOD OF TREATING ENDOTHELIAL DYSFUNCTION
    Publication number: 20130130978
    Abstract: Endothelial dysfunction (ED) is associated with a number of diseases and disorders. Agonists of the non-proteolytically activated thrombin receptor can be used in methods to treat ED or ED-related diseases and disorders.
    Type: Application
    Filed: November 20, 2012
    Publication date: May 23, 2013
    Applicants: The Texas A&M University System, The Board of Regents, The University of Texas System
    Inventors: The Board of Regents, The University of Texas, The Texas A&M University System
  • High Concentration Baclofen Preparations
    Publication number: 20130131176
    Abstract: Stable aqueous solutions comprising concentrations of baclofen in the range of greater than 2.0 mg/mL up to about 10 mg/mL are disclosed. These solutions can be used as pharmaceuticals for parenteral or oral administration. The invention also provides methods of preparing said stable aqueous baclofen solutions.
    Type: Application
    Filed: January 16, 2013
    Publication date: May 23, 2013
    Applicant: Board of Regents, The University of Texas System
    Inventors: Lawrence A. Trissel, Yanping Zhang
  • Heterocyclic modulators of cannabinoid receptors
    Patent number: 8440832
    Abstract: Heterocyclic compounds which modulate cannabinoid receptors are presented. Pharmaceutical compositions containing these compounds, methods of using these compounds as modulators of cannabinoid receptors and processes for synthesizing these compounds are also described herein.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: May 14, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventors: Mohamed Naguib Attala, Philippe Diaz
  • Micro-RNA family that modulates fibrosis and uses thereof
    Patent number: 8440636
    Abstract: The present invention relates to the identification of a microRNA family, designated miR-29a-c, that is a key regulator of fibrosis in cardiac tissue. The inventors show that members of the miR-29 family are down-regulated in the heart tissue in response to stress, and are up-regulated in heart tissue of mice that are resistant to both stress and fibrosis. Also provided are methods of modulating expression and activity of the miR-29 family of miRNAs as a treatment for fibrotic disease, including cardiac hypertrophy, skeletal muscle fibrosis other fibrosis related diseases and collagen loss-related disease.
    Type: Grant
    Filed: July 31, 2008
    Date of Patent: May 14, 2013
    Assignee: The Board of Regents, The University of Texas System
    Inventors: Eric Olson, Eva van Rooij
  • Methods and apparatus for design and control of multi-port power electronic interface for renewable energy sources
    Patent number: 8442698
    Abstract: Methods and systems for energy management are disclosed. An example system includes a first port connected to an energy storage device for bidirectional flow of energy, a second port connected to an energy source device for unidirectional flow of energy, a third port connected to a utility grid for bidirectional flow of energy, and a unified control system with control logic configured to simultaneously control energy flow between the first, second, and third ports based on at least two factors from the group consisting of: a state of charge of the energy storage device, a state of the energy source device, and a state of the utility grid. Other embodiments are described and claimed.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: May 14, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventors: Babak Fahimi, Wei Jiang
  • Chlamydial antigens as reagents for diagnosis and treatment of chlamydial infection and disease
    Patent number: 8440208
    Abstract: The present invention provides Chlamydia proteins and methods of use in diagnostic and detection assays as well as in treatment and immunization protocols.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: May 14, 2013
    Assignee: Board of Regents, The University of Texas System
    Inventor: Guangming Zhong
  • Methods and compositions for vaccination comprising nucleic acid and/or polypeptide sequences of
    Patent number: 8435533
    Abstract: The instant invention relates to antigens and nucleic acids encoding such antigens obtainable by screening a Chlamydia genome. In more specific aspects, the invention relates to methods of isolating such antigens and nucleic acids and to methods of using such isolated antigens for producing immune responses. The ability of an antigen to produce an immune response may be employed in vaccination or antibody preparation techniques.
    Type: Grant
    Filed: September 26, 2012
    Date of Patent: May 7, 2013
    Assignees: Auburn University, Board of Regents, The University of Texas System
    Inventors: Stephen A. Johnston, Katherine Stemke-Hale, Kathryn F. Sykes, Bernhard Kaltenboeck