Abstract: An animal restraint jacket includes an elongated sheet formed of a fabric which is stretchable in the longitudinal direction. A pair of leg holes are formed in the sheet proximal to and spaced from the opposing ends of the sheet, such that the jacket is fastened along the chest of the animal. An aperture is formed in the sheet midway between the ends, and a pair of elastic straps are attached at their ends adjacent the aperture, to receive and hold a catheter or other medical device extending through the aperture. A flap is attached along one side edge to the sheet and extends to cover the aperture and elastic straps, and any medical device secured under the straps.