Patents Assigned to Board of Supervisors for the University of Louisia System, acting on behalf of the University of Lou
  • Inhibitors of Metastasis, Methods of Generating Such Inhibitors and Their Therapeutic Applications
    Publication number: 20140286952
    Abstract: The chain of events that explains calcitonin receptor (CTR)-stimulated invasion and metastasis of prostate cancer cells was identified. The CTR-stimulated events depend on the interaction of CTR with the PDZ3 domain of ZO-1. Small peptides and small molecules were identified that inhibit this interaction. The small inhibitory peptides were synthesized and can be used to attenuate or inhibit metastasis in solid cancer tumors.
    Type: Application
    Filed: March 30, 2012
    Publication date: September 25, 2014
    Applicant: Board of Supervisors for the University of Louisia System, acting on behalf of the University of Lou
    Inventor: Girish V. Shah