Abstract: Provided are compounds, pharmaceutical compositions, cosmetic and dermatological compositions or nutritional supplement compositions, comprising omega-3 very-long-chain polyunsaturated fatty acids (n-3 VLC-PUFAs) and/or their endogenous hydroxylated derivatives thereof, known as elovanoids. This disclosure provides methods for neuroprotection, organ and tissue protection or restoration, prevention or slowing down of aging-related diseases and conditions, and sustainment of function during the aging process.
Type:
Grant
Filed:
September 19, 2019
Date of Patent:
June 27, 2023
Assignees:
Board of Supervisors of Lousiana State University and Agricultural and Mechanical College, University of Southern California
Abstract: The present disclosure provides for shape memory proppants, methods for making shape memory proppants, and methods of using shape memory proppants, and the like. The strong expandable proppants of the present disclosure may be used in maintaining fracture openings.
Type:
Grant
Filed:
May 24, 2018
Date of Patent:
January 21, 2020
Assignee:
BOARD OF SUPERVISORS OF LOUSIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Inventors:
Arash Dahi Taleghani, Amir Shojaei, Guoqiang Li
Abstract: An simpler, cheaper method for enhancing the percentage of eicosapentaenoic acid (EPA) and/or docosahexaenoic acid (DHA) from source oils has been discovered. This method hydrolyzes the oil using the lipase enzyme but does not inactivate the lipase enzyme with either added chemicals or increased temperature. The method relies on centrifugation to separate the enzyme from the desired oil and separate the oil from aqueous impurities. The hydrolyzed oil is enhanced with EPA and DHA, and can be further purified by using activated surface adsorbents, e.g., activated alumina, to remove more free fatty acids and impurities.
Type:
Application
Filed:
September 19, 2012
Publication date:
November 13, 2014
Applicant:
Board of Supervisors of Lousiana State University and Agricultural and Mechanical College
Abstract: A recombinant herpes simplex virus type-1 (HSV-1) has been constructed that carries a deletion of one of the two viral ?1 34.5 genes and other immediate early genes, which render the virus able to selectively replicate in cancer cells but not efficiently replicate in normal cells, and in which specific mutations have been introduced to enable the virus to spread among cancer cells by virus-induced fusion. Specifically, syncytial mutations have been introduced in the genes coding for glycoprotein B and glycoprotein K of the virus, enabling high replication and spread of the virus in cancer cells in the presence of substantially lower amounts of ?1 34.5 protein, which is required for optimum infectious virus produced and virus-induced cell fusion. These altered viruses or the isolated bacterial chromosomes could be used to treat various cancers including breast, liver, colon, and other tissues.
Type:
Grant
Filed:
May 9, 2008
Date of Patent:
November 19, 2013
Assignee:
Board of Supervisors of Lousiana State University and Agricultural and Mechanical College
Abstract: A method for generating metallic nanomaterials using acetylenic-bridged metal-carbonyl complexes as a precursor allows control of nanoparticle properties. The novel method produced metallic nanomaterials resistant to oxidation.
Type:
Grant
Filed:
September 14, 2007
Date of Patent:
April 9, 2013
Assignee:
Board of Supervisors of Lousiana State University And Agricultural and Mechanical College
Inventors:
Challa S. S. R. Kumar, Rohini M. de Silva, Josef Hormes
Abstract: A method or kit for modifying the excretory behavior of animals such as dogs. It has been discovered that placing .beta.-ionone in a particular location induces dogs to urinate and defecate preferentially at or near that location. Related compounds which may also be useful, in lieu of .beta.-ionone, or as synergists, are also disclosed.
Type:
Grant
Filed:
May 19, 1993
Date of Patent:
February 22, 1994
Assignee:
Board of Supervisors of Lousiana State University and Agricultural and Mechanical College