Abstract: A method of preventing or reducing the occurrence and/or development of a hernia within a subject at risk of developing a hernia includes implanting a graft material in contact with an opening in an abdominal wall. The graft material promotes healing of the abdominal wall and includes placental or placental derived tissue.
Type:
Application
Filed:
March 27, 2020
Publication date:
October 22, 2020
Applicant:
The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
Frank Ho Pak Lau, Ian Hodgdon, Michael Cook
Abstract: The present disclosure provides compositions comprising a lyn kinase activator and TRPM8 agonist, and to methods of: reducing blood glucose levels, weight gain, or fat depot levels; treating metabolic syndrome, Syndrome X, obesity, prediabetes, type II diabetes, type I diabetes; treating hypercholesterolemia, hypertension, coronary heart disease, diabetic neuropathy, lipodystrophy, diabetic retinopathy, erectile dysfunction, kidney disease, dyslipidemia, dyslipoproteinemia, a peroxisome proliferator activated receptor-associated disorder, septicemia, a thrombotic disorder, or pancreatitis; inducing the beiging of adipocytes; and preventing pancreatic beta cell degeneration.
Type:
Grant
Filed:
April 9, 2018
Date of Patent:
September 29, 2020
Assignees:
Melior Pharmaceuticals I, Inc., Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
Andrew G. Reaume, Weina Cong, Frank Greenway, Ann Coulter
Abstract: The poor water solubility of high molecular weight chitosan has limited its use in areas such as food and beverage products, post-harvest treatments, cosmetic and pharmaceutical products, medical treatments, and environmental pollution treatments. Disclosed is a high-molecular-weight, solid-state chitosan powder that is completely water-soluble.
Type:
Application
Filed:
November 14, 2016
Publication date:
August 13, 2020
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: A composition comprising thermoset polymer, shape memory polymer to facilitate macro scale damage closure, and a means for molecular scale healing is disclosed; the composition has the ability to resolve structural defects by a bio-mimetic close-then heal process. In use, the shape memory polymer serves to bring surfaces of a structural defect into approximation, whereafter use of the means for molecular scale healing allowed for movement of the healing means into the defect and thus obtain molecular scale healing. The means for molecular scale healing can be a thermoplastic such as fibers, particles or spheres which are used by heating to a level at or above the thermoplastic's melting point, then cooling of the composition below the melting temperature of the thermoplastic. Compositions of the invention have the ability to not only close macroscopic defects, but also to do so repeatedly even if another wound/damage occurs in a previously healed/repaired area.
Type:
Application
Filed:
April 17, 2020
Publication date:
August 6, 2020
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: Mogrosides may be used as a flavor modifier in various foods, beverages, pharmaceutical compositions, and the like to block the perception of bitter and astringent flavors or other off flavors.
Type:
Application
Filed:
March 18, 2020
Publication date:
July 9, 2020
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
John W. Finley, Darryl Holliday, Joan M. King, Alfredo D. Prudente, JR.
Abstract: Disclosed is a less expensive, more efficient process for enhanced oil recovery, particularly useful in high cost environments such as offshore. This process is known as single well gas assisted gravity drainage (SW-GAGD). The process comprises the steps of drilling from a single wellbore one or more horizontal laterals near the bottom of a payzone and injecting a fluid displacer such as nitrogen or carbon dioxide through injection points. The injectant sweeps the oil and other produced fluids in the reservoir towards other producing perforations in the single well.
Type:
Grant
Filed:
May 9, 2016
Date of Patent:
July 7, 2020
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: A method of treating a condition of in a human patient comprising pharmacologically activating a translocator protein of 18 kDa (TSPO), wherein the condition is one of a chronic methamphetamine addiction, a medical consequence of methamphetamine use; a behavioral consequence of methamphetamine use, an HIV associated cognitive motor disorder, an HIV-associated neurodegenerative disorder, and a neuroinflammatory response.
Type:
Grant
Filed:
June 4, 2018
Date of Patent:
July 7, 2020
Assignee:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY and Agricultural and Mechanical College
Inventors:
Nicholas E. Goeders, Christopher Dalton Schmoutz
Abstract: Methods and compositions for treating a lysosomal movement associated disease in an animal, in which the position of lysosomes can influence disease progression, comprising administering an effective amount of a first lysosome migration inhibitor or a pharmaceutically acceptable salt, solvate, clathrate, stereoisomer, enantiomer or prodrug thereof.
Type:
Grant
Filed:
May 6, 2016
Date of Patent:
June 30, 2020
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
James Allen Cardelli, Magdalena Liliana Circu, Samantha Sarah Dykes, Hazem Edmond El-Osta
Abstract: A composition comprising thermoset polymer, shape memory polymer to facilitate macro scale damage closure, and a component for molecular scale healing has the ability to repair structural defects by a bio-mimetic, close-then-heal process. The shape memory polymer serves to bring surfaces of a structural defect into proximity, after which the healing component moves into the defect and provides molecular scale healing. The component for molecular scale healing can be a thermoplastic, such as fibers, particles or spheres, which are heated to or above the thermoplastic's melting point, and then the composition is cooled below that melting temperature. The compositions can not only close macroscopic defects, but they can also do so repeatedly even if damage recurs in a previously healed/repaired area.
Type:
Grant
Filed:
March 14, 2019
Date of Patent:
June 30, 2020
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: The herbicide-tolerant rice cultivar designated “PVL01” and its hybrids and derivatives are disclosed. The present invention provides a method for producing rice, wherein said rice is tolerant to a quizalofop herbicide or tolerant to a tepraloxdyim herbicide; wherein said rice belongs to any of (a) variety “PVL01” or (b) a hybrid, derivative, or progeny of “PVL01”. Further provided are methods for producing a hybrid or a new variety by crossing the rice variety “PVL01” with another rice line, one or more times. In another embodiment, this invention allows for single-gene converted plants of “PVL01”. In another embodiment, this invention provides regenerable cells for use in tissue culture of rice plant “PVL01”.
Type:
Application
Filed:
June 19, 2018
Publication date:
June 25, 2020
Applicant:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: Methods, compositions, devices, and kits are described herein that are useful for detecting BoHV-1 infection in animals and/or for distinguishing animals that may benefit from administration of BoHV-1 tmv vaccine.
Type:
Grant
Filed:
July 31, 2015
Date of Patent:
June 23, 2020
Assignee:
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Abstract: The invention is directed generally to oligonucleotide compositions for the treatment of DNA repeat expansion diseases. The invention also relates to oligonucleotides directed to subunits of the DNA mismatch repair system.
Type:
Grant
Filed:
November 7, 2016
Date of Patent:
June 2, 2020
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: Methods and apparatus are disclosed relating to the stimulating of tissue including nerve tissue based on combinations of capacitors and resistors. Application and removal of voltage to an electrical circuit is taught as part of a method of creating voltage waveforms for nerve and other tissue with such waveforms creating neural signals. The electrical circuits taught may, include a first electrical node grounded through a first resistor; a second electrical node grounded through a second resistor; a first capacitor connected to both the first electrical node and the second electrical node; a second capacitor separating the second electrical node from a biological grounding point and direct current sources connected to the two nodes.
Type:
Grant
Filed:
November 8, 2016
Date of Patent:
June 2, 2020
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
Jose A. Parodi Amaya, Edward F Austin, Jin-Woo Choi
Abstract: A new variety of sweetpotato, identified as ‘LA17-120’, is disclosed having resistance to southern root-knot nematode; a purple flesh storage root and attractive 5-lobed green leaves with purple vines.
Type:
Grant
Filed:
February 8, 2019
Date of Patent:
July 14, 2020
Assignee:
THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Abstract: A new variety of sweetpotato, identified as ‘LA17-40’, is disclosed having resistance to southern root-knot nematode; an orange flesh and attractive 5 lobed dark green and purple leaves.
Type:
Grant
Filed:
February 8, 2019
Date of Patent:
July 14, 2020
Assignee:
THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Abstract: A new variety of sweetpotato, identified as ‘LA08-21P’, is disclosed having resistance to both Fusarium wilt and southern root knot nematode; a light purple-banded flesh and deep-purple skin, and moderately high yield characteristics.
Type:
Grant
Filed:
February 8, 2019
Date of Patent:
July 14, 2020
Assignee:
THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Inventors:
Don R. LaBonte, Arthur Q. Villordon, Christopher A. Clark
Abstract: A new variety of sweetpotato, identified as ‘LA17-54’, is disclosed having disease resistance to Fusarium wilt; an orange flesh, red-copper skin storage root and attractive purple, red-hued and green leaves with purple venation and purple vines.
Type:
Grant
Filed:
February 8, 2019
Date of Patent:
July 21, 2020
Assignee:
THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Abstract: A new variety of sweetpotato, identified as ‘LA17-31’ is disclosed having resistance to southern root-knot nematode and Fusarium wilt; an orange flesh, red-purple skin storage root and attractive zero to three or five lobed dark green leaves with purple venation and purple vines.
Type:
Grant
Filed:
February 8, 2019
Date of Patent:
July 28, 2020
Assignee:
THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Abstract: A new variety of sweetpotato, identified as ‘LA13-81’, is disclosed having disease resistance to both Fusarium wilt and Streptomyces soil rot; an orange flesh storage root and deep red-purple skin, and high yield characteristics.
Type:
Grant
Filed:
February 8, 2019
Date of Patent:
July 28, 2020
Assignee:
THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE
Inventors:
Don R. LaBonte, Arthur Q. Villordon, Tara P. Smith, Christopher A. Clark