Patents Assigned to Board of Trustees of Leland S. Stanford Jr. Univ.
  • Regulated apoptosis
    Patent number: 6054436
    Abstract: We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: April 25, 2000
    Assignees: Board of Trustees of Leland S. Stanford Jr. Univ., President & Fellows of Harvard College
    Inventors: Gerald R. Crabtree, Stuart L. Schreiber, David M. Spencer, Thomas J. Wandless, Peter Belshaw
  • Regulated apoptosis
    Patent number: 5994313
    Abstract: We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 30, 1999
    Assignees: Board of Trustees of the Leland S. Stanford, Jr. Univ., President and Fellows of Harvard College
    Inventors: Gerald R. Crabtree, Stuart L. Schreiber, David M. Spencer, Thomas J. Wandless, Peter Belshaw