Patents Assigned to Board of Trustees of Leland Stanford Junior University
  • Methods for treatment of headaches by administration of oxytocin
    Patent number: 8252745
    Abstract: The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: August 28, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Trigemina, Inc., HealthPartners Research Foundation
    Inventors: David C. Yeomans, Martin S. Angst, William H. Frey, II, Daniel I. Jacobs
  • Method of treating multiple sclerosis with phosphocholine containing lipids
    Patent number: 8252775
    Abstract: To perform large-scale multiplex analysis of lipid-specific binding, lipid microarrays were developed. Lipids identified as disease associated, or analogs there, can be tolerogenic to patients suffering from autoimmune disease. Lipid array analysis has revealed anti-lipid antibodies in patients with immune disorders, and may contribute to the pathogenesis of disease.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: August 28, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, U.S. Department of Veteran Affairs
    Inventors: Jennifer L. Kanter, William H. Robinson, Lawrence Steinman
  • Single-walled carbon nanotubes and methods of preparation thereof
    Patent number: 8252405
    Abstract: The present invention provides single-walled carbon nanotubes and systems and methods for their preparation.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: August 28, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Hongjie Dai, David Mann, Guangyu Zhang
  • Method for Implementing a High-Level Image Representation for Image Analysis
    Publication number: 20120213426
    Abstract: Robust low-level image features have been proven to be effective representations for a variety of visual recognition tasks such as object recognition and scene classification; but pixels, or even local image patches, carry little semantic meanings. For high-level visual tasks, such low-level image representations are potentially not enough. The present invention provides a high-level image representation where an image is represented as a scale-invariant response map of a large number of pre-trained generic object detectors, blind to the testing dataset or visual task. Leveraging on this representation, superior performances on high-level visual recognition tasks are achieved with relatively classifiers such as logistic regression and linear SVM classifiers.
    Type: Application
    Filed: February 22, 2011
    Publication date: August 23, 2012
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Li Fei-Fei, Li-Jia Li, Hao Su
  • MICRORESONATOR OPTICAL SWITCH HAVING NANOPARTICLES AND METHOD OF OPTICAL SWITCHING
    Publication number: 20120213471
    Abstract: An optical switch includes a microresonator comprising a plurality of silicon nanoparticles within a silicon-rich silicon oxide layer. The microresonator further includes an optical coupler optically coupled to the microresonator and configured to be optically coupled to a pump source and to a signal source. A method of optical switching includes providing an optical switch comprising an optical coupler and a microresonator having a plurality of nanoparticles and receiving an optical pulse by the optical switch, wherein at least a portion of the optical pulse is absorbed by the nanoparticles such that at least a portion of the microresonator undergoes an elevation of temperature and a corresponding refractive index change when the optical pulse has an optical power greater than a predetermined threshold level.
    Type: Application
    Filed: April 23, 2012
    Publication date: August 23, 2012
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Michel J.F. Digonnet, Anuranjita Tewary, Mark Brongersma
  • Method and System for Touch-Free Control of Devices
    Publication number: 20120212413
    Abstract: The present invention provides a system and computerized method for receiving image information and translating it to computer inputs. In an embodiment of the invention, image information is received for a predetermined action space to identify an active body part. From such image information, depth information is extracted to interpret the actions of the active body part. Predetermined gestures can then be identified to provide input to a computer. For example, gestures that can be interpreted to mimic computerized touchscreen operation. Also, touchpad or mouse operations can be mimicked.
    Type: Application
    Filed: February 17, 2011
    Publication date: August 23, 2012
    Applicant: The Board of Trustees of the Leland Stanford, Junior, University
    Inventors: Christian Plagemann, Hendrik Dahlkamp, Hariraam Varun Ganapathi, Sebastian Thrun
  • DIAMONDOID MONOLAYERS AS ELECTRON EMITTERS
    Publication number: 20120212153
    Abstract: Provided are electron emitters based upon diamondoid monolayers, preferably self-assembled higher diamondoid monolayers. High intensity electron emission has been demonstrated employing such diamondoid monolayers, particularly when the monolayers are comprised of higher diamondoids. The application of such diamondoid monolayers can alter the band structure of substrates, as well as emit monochromatic electrons, and the high intensity electron emissions can also greatly improve the efficiency of field-effect electron emitters as applied to industrial and commercial applications.
    Type: Application
    Filed: April 9, 2012
    Publication date: August 23, 2012
    Applicants: The Regents of the University of California, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Wanli YANG, Jason D. Fabbri, Nicholas A. Melosh, Zahid Hussain, Zhi-Xun Shen
  • Hydrophobic nanotubes and nanoparticles as transporters for the delivery of drugs into cells
    Patent number: 8246995
    Abstract: Methods and materials for delivering biologically active molecules to cells in vitro or in vivo are provided. The methods and materials use carbon nanotubes or other hydrophobic particles, tubes and wires, functionalized with a linking group that is covalently bound to the nanotubes, or, alternatively, to the biologically active molecule, such as a protein. The biologically active molecule is preferably released from the nanotube when the complex has been taken up in an endosome.
    Type: Grant
    Filed: May 9, 2006
    Date of Patent: August 21, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Hongjie Dai, Nadine Wong Shi Kam, Paul A. Wender, Zhuang Liu
  • Variable imaging arrangements and methods therefor
    Patent number: 8248515
    Abstract: Various approaches to imaging involve selecting directional and spatial resolution. According to an example embodiment, images are computed using an imaging arrangement to facilitate selective directional and spatial aspects of the detection and processing of light data. Light passed through a main lens is directed to photosensors via a plurality of microlenses. The separation between the microlenses and photosensors is set to facilitate directional and/or spatial resolution in recorded light data, and facilitating refocusing power and/or image resolution in images computed from the recorded light data. In one implementation, the separation is varied between zero and one focal length of the microlenses to respectively facilitate spatial and directional resolution (with increasing directional resolution, hence refocusing power, as the separation approaches one focal length).
    Type: Grant
    Filed: February 6, 2007
    Date of Patent: August 21, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Yi-Ren Ng, Patrick M. Hanrahan, Mark A. Horowitz, Marc S. Levoy
  • Role of miRNA in T cell leukemia
    Patent number: 8247388
    Abstract: The ability of miR-181a to support active signaling between Notch and pre-TCR pathways by coordinately dampening negative regulators of these pathways allows the use of miR-181a as a therapeutic target for T-ALL.
    Type: Grant
    Filed: June 8, 2009
    Date of Patent: August 21, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Chang-Zheng Chen, Tin Mao
  • Neoplasia targeting peptides and methods of using the same
    Patent number: 8247529
    Abstract: The present invention provides compositions including neoplasia targeting peptides as well as methods of using the neoplasia targeting peptides in diagnosing, detecting, treating, monitoring treatment, and analyzing cancer or cancer cells in vivo and in vitro.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: August 21, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Thomas D. Wang, Shaoying Lu
  • Optical structure on an optical fiber and method of fabrication
    Patent number: 8249400
    Abstract: An optical structure on an optical fiber and a method of fabrication is provided. The optical structure includes an end of an optical fiber and a layer formed on the end of the optical fiber. The layer comprises one or more first portions having a first optical pathlength in a direction perpendicular to the layer and one or more second portions having a second optical pathlength in the direction perpendicular to the layer, the second optical pathlength different from the first optical pathlength.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: August 21, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Onur Kilic, Michel J. F. Digonnet, Gordon S. Kino, Olav Solgaard, Shrestha Basu Mallick, Onur Can Akkaya
  • Modifying catalytic behavior of nanocrystals
    Patent number: 8247318
    Abstract: The present invention provides a method of providing a desired catalyst electron energy level. The method includes providing a donor material quantum confinement structure (QCS) having a first Fermi level, and providing an acceptor QCS material having a second Fermi level, where the first Fermi level is higher than the second Fermi level. According to the method the acceptor is disposed proximal to the donor to alter an electronic structure of the donor and the acceptor materials to provide the desired catalyst electron energy level.
    Type: Grant
    Filed: January 21, 2010
    Date of Patent: August 21, 2012
    Assignees: The Board of Trustees of the Leland Stanford Junior University, Honda Motor Co., Ltd
    Inventors: Timothy P. Holme, Friedrich B. Prinz
  • System for mobile station positioning
    Patent number: 8244174
    Abstract: Mobile station positioning is implemented using various methods and devices. According to one example embodiment of the present invention, an azimuth angle estimation of the location of a mobile station is accomplished using a radio-signal processing apparatus. The azimuth angle is estimated with respect to a nearby base station that covers a service area using common sectorization via multiple directional antennas respectively transmitting at different azimuth angles. The apparatus has a memory for storing information that associates directional sector antennas of the nearby base station and expected antenna radiation gains in the common sectorization service area corresponding to locations relative to the nearby base station.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: August 14, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventor: Seung Hyun Kong
  • Regenerative dot cells
    Patent number: 8241898
    Abstract: Methods and compositions are provided for the isolation, culture and use of highly regenerative somatic mammalian cells. The cells are very small, and have an undefined nuclear structure. The cells may be isolated from fetal or adult tissues, and are found in tissue including, without limitation, fetal dermal tissue, blood, and bone marrow. The cells are characterized as expressing one or more markers selected from E-cadherin, integrin ?1, CXCR4, CD90 and CD34, and may be selected on the basis of such expression patterns.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: August 14, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Wuyi Kong, Shaowei Li, Peter Lorenz
  • Correction of optical aberrations
    Patent number: 8243157
    Abstract: Digital images are computed using an approach for correcting lens aberration. According to an example embodiment of the present invention, a digital imaging arrangement implements microlenses to direct light to photosensors that detect the light and generate data corresponding to the detected light. The generated data is used to compute an output image, where each output image pixel value corresponds to a selective weighting and summation of a subset of the detected photosensor values. The weighting is a function of characteristics of the imaging arrangement. In some applications, the weighting reduces the contribution of data from photosensors that contribute higher amounts of optical aberration to the corresponding output image pixel.
    Type: Grant
    Filed: February 6, 2007
    Date of Patent: August 14, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Yi-Ren Ng, Patrick M. Hanrahan, Mark A. Horowitz, Marc S. Levoy
  • Apparatus and methods using hollow-core fiber tapers
    Patent number: 8244086
    Abstract: An optical device and methods of using an optical device are provided. The optical device includes a hollow-core fiber including a first portion and a second portion. The first portion includes a hollow core having a first diameter. The second portion includes a hollow core having a second diameter smaller than the first diameter. The difference between the first diameter and the second diameter is less than 10% of the first diameter.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: August 14, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Michel J. F. Digonnet, Aydogan Ozcan
  • Non-invasive cardiac monitor and methods of using continuously recorded cardiac data
    Patent number: 8244335
    Abstract: Embodiments of the present invention provide a method of analyzing cardiac information by collecting a plurality of self-contained, wearable, portable cardiac monitors each of the cardiac monitors electronically storing at least 24 hours of continuously detected and unanalyzed cardiac signals from a mammal. Next, retrieving cardiac information stored in each of the plurality of self-contained portable cardiac monitors. Next, forwarding retrieved cardiac information.
    Type: Grant
    Filed: February 6, 2007
    Date of Patent: August 14, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Uday N. Kumar, Joseph A. Knight, Kit Yee Au-Yeung, John Warren White
  • METHODS OF MONITORING ENDOPLASMIC RETICULUM (ER) STRESS RESPONSE
    Publication number: 20120202751
    Abstract: Transgenic mammals, cells derived from the animals, and methods of using these to monitor the endoplasmic reticulum (ER) stress response are provided. In some embodiments, the methods allow for monitoring the ER stress response in real time. Some of the methods allow non-invasive in vivo visualization of ER stress response. Also provided are methods of screening molecules and/or treatment conditions for the ability to modulate the ER stress response, methods of treating diseases characterized by ER stress response activity, and methods of detecting the toxicity or therapeutic ratio of molecules that modulate the ER stress response.
    Type: Application
    Filed: August 10, 2010
    Publication date: August 9, 2012
    Applicant: The Board of trustees of the Leland Stanford Junior University
    Inventors: Albert C. Koong, Michael T. Spiotto, George P. Yang
  • Method and device for non-thermal electrically-induced closure of blood vessels by occlusion
    Patent number: 8235989
    Abstract: Methods and devices for the non-thermal, electrically-induced temporary or permanent closure of blood vessels. Methods and devices employ pulsed electrical energy according to a defined regime to effect controlled occlusion of targeted blood vessels without heating the vessel and with minimal damage to adjacent tissue. The extent of vessel closure, i.e., temporary (vasoconstriction) or permanent (thrombosis), is controlled based on the manipulation of various parameters of the electrical stimulation regime as well as the configuration of the electrodes used to apply the regime.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: August 7, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Daniel V. Palanker, Alexander B. Vankov