Abstract: Described herein are expression cassettes, plant cells, plant seeds, plants, and methods useful for improving the glucan content and growth of plants.
Type:
Grant
Filed:
May 3, 2019
Date of Patent:
June 13, 2023
Assignee:
Board of Trustees of Michigan State University
Inventors:
Federica Brandizzi, Sang Jin Kim, Starla Zemelis-Durfee
Abstract: A fusion chimeric protein is described herein that can assemble a functional carboxysome core, which is able to fix carbon by taking atmospheric carbon dioxide and converting it into useful carbon-containing compounds such as 3-phosphoglycerate (3-PGA).
Type:
Grant
Filed:
October 31, 2019
Date of Patent:
June 13, 2023
Assignee:
Board of Trustees of Michigan State University
Abstract: Plants, plant cells, and seeds are described herein that grow well and are resistant to environmental stresses such as drought and insects, where the plants have one or more mutations that reduce or eliminate the interaction of MYC transcription factors with the JAZ proteins. The plants can have an additional mutation that reduces or eliminates the function of the PHYB gene, and/or a heterologous PIF4 transgene or PIF4 expression cassette to improve the growth of the myc mutant plants. Methods of making and using such plants, plant cells, and seeds are also described.
Type:
Grant
Filed:
August 25, 2017
Date of Patent:
June 13, 2023
Assignee:
Board of Trustees of Michigan State University
Inventors:
Gregg A. Howe, Marcelo Campos, Yuki Yoshida
Abstract: Described herein are compositions and methods that involve use of omega-3 polyunsaturated fatty acids (e.g., fish oil and/or flax oil) as supplements to colostrum. When administered to newborn calves the combination of colostrum with fish oil and/or flax oil can improve the health and immune function of the calf.
Type:
Grant
Filed:
June 19, 2020
Date of Patent:
June 6, 2023
Assignee:
Board of Trustees of Michigan State University
Abstract: New systems and methods allow for transmission of multiple types of content protocols over a unidirectional content delivery network, such as a television broadcast. Hardware and/or software used at the network transmission location (such as a television broadcast station) and hardware and/or software located at an endpoint (such as a home television, car infotainment system, or first responder location) allow for a native ATSC 1.0 signal to have embedded within it additional content that is not encoded as ATSC 1.0 content. The non-ATSC 1.0 content can be detected and segregated from ATSC 1.0 content so that the endpoint devices (such as a television receiver) will not attempt to render the non-ATSC 1.0 content (such as, e.g., ATSC 3.0 content or application specific content) as normal ATSC 1.0 programming. Instead, the non-ATSC 1.
Type:
Grant
Filed:
January 4, 2021
Date of Patent:
June 6, 2023
Assignee:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Inventors:
Chandra Kotaru, Prabu David, Susanne Elkins
Abstract: The disclosure relates to an electrolyzer reactor suitable for the reduction of organic compounds. The reactor includes a membrane electrode assembly with freestanding metallic meshes which serve both as metallic electrode structures for electron transport as well as catalytic surfaces for electron generation and organic compound reduction. Suitable organic compounds for reduction include oxygenated and/or unsaturated hydrocarbon compounds, in particular those characteristic of bio-oil (e.g., alone or a multicomponent mixtures). The reactor and related methods provide a resource- and energy-efficient approach to organic compound reduction, in particular for bio-oil mixtures which can be conveniently upgraded at or near their point of production with minimal or no transportation.
Type:
Grant
Filed:
April 10, 2020
Date of Patent:
June 6, 2023
Assignee:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Inventors:
James E. Jackson, Chun Ho Lam, Christopher M. Saffron, Dennis J. Miller
Abstract: A multilayer composite includes adjacent filler layers having a filler material dispersed within a first polymeric matrix and an intervening-layer disposed between the adjacent filler layers. The intervening-layer comprises nanoplatelets embedded within a second polymeric matrix and are aligned substantially parallel to the adjacent filler layers. The intervening-layer is configured to fail upon application of a force to the multilayer composite that is greater than or equal to a predetermined force threshold.
Type:
Grant
Filed:
April 29, 2016
Date of Patent:
May 30, 2023
Assignee:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Abstract: The disclosure relates to processes, related polyacid polymers, and related articles for functionalizing a porous membrane by contacting the membrane with a polyacid polymer at low pH to stably adsorb a polyacid layer on the membrane pore surface, in particular polyacid polymers including repeating units with a pendent metal-binding ligand or star polyacid polymers. The resulting functionalized membrane is characterized by a high density of free acid groups, resulting in a higher specific capacity for its intended application. The process allows functionalization of porous membranes in a very simple, one-step process, for example without a need to derivatize an adsorbed polyacid layer to impart metal-binding ligand functionality thereto. Such functional membranes may find multiple uses, including rapid, selective binding of proteins for their purification or immobilization.
Type:
Grant
Filed:
September 15, 2020
Date of Patent:
May 23, 2023
Assignee:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Inventors:
Merlin L. Bruening, Salinda Wijeratne, Wenjing Ning, Jinlan Dong, Weijing Liu
Abstract: The present invention relates to compositions and methods for modulating immune responses using at least one CRACC composition comprising an adenoviral vector comprising at least one CRACC fusion. Such CRACC compositions may be combined with a number of other therapeutic agents which target modulating immune responses, as well as, treatments that include immune events.
Type:
Grant
Filed:
September 18, 2019
Date of Patent:
May 16, 2023
Assignee:
Board of Trustees of Michigan State University
Abstract: An apparatus including a controllable fluid-contacting surface is provided. In another aspect, the present apparatus includes a flexible membrane and multiple actuators each having an output shaft or activation member coupled to a water-contacting membrane, with the shafts extending in a direction offset from the nominal outer surface of the membrane. A further aspect of the present apparatus includes an underwater vessel including a propulsion source, a flexible membrane having a water-contacting outer surface and an electronic controller including programmable software for actuating the actuators.
Type:
Grant
Filed:
October 29, 2019
Date of Patent:
May 9, 2023
Assignees:
The Government of the USA represented by the Sec. of the Navy, Board of Trustees of Michigan State University
Inventors:
Xaiobo Tan, Thassyo Da Silva Pinto, Demetris Coleman, Weilin Hou, Silvia Matt, Sergio Restaino, Freddie Santiago, Hongyang Shi
Abstract: A control circuit is provided for a field-effect transistor with a floating source node. The control circuit includes: a charge storage device electrically connected between a gate of the field-effect transistor and a DC power supply; a gate control circuit electrically connected between the charge storage device and the gate of the field-effect transistor; and a charge control circuit electrically connected between the DC power supply and the charge storage device. The gate control circuit is configured to receive a gate control signal and operates to turn on the field-effect transistor during on time of the gate control signal and turn off the field-effect transistor during off time of the gate control signal. The charge control circuit is also configured to receive the gate control signal and operates to charge the charge storage device with power from the DC power supply during off time of the gate control signal.
Type:
Application
Filed:
October 25, 2022
Publication date:
May 4, 2023
Applicant:
Board of Trustees of Michigan State University
Abstract: The multi-modal imaging system, in particular for brain imaging, comprising a pump signal generator which emits at least one pump signal in the radio frequency (RF)-range with a first power P1 and a second power P2, a wireless detection unit, which comprises at least one parametric resonator circuit with multiple resonance modes, wherein the at least one parametric resonator circuit comprises at least two varactors, at least one capacitor and at least one inductance, wherein, in a first detection mode, the pump signal, having a first power P1, induces a first pump current in the at least one parametric resonator circuit, wherein the at least one parametric resonator circuit is operated below its oscillation threshold and generates a first output signal by amplifying a first input signal, which is provided due to a magnetic-resonance (MR) measurement, wherein an external receiving device receives the first output signal, wherein, in a second detection mode, the pump signal, having a second power P2, induces a
Type:
Grant
Filed:
June 12, 2019
Date of Patent:
April 25, 2023
Assignees:
The General Hospital Corporation, Board of Trustees Michigan State University
Abstract: A system may perform speech enhancement of audio data in real-time by suppressing noise components that are present in the audio data while preserving speech components. The system may include an in-ear module and a separate signal processing module that is wirelessly communicatively coupled to the in-ear module. The system may include non-negative matrix factorization (NMF) dictionaries capable of identifying frequency band components associated with speech and frequency band components associated with noise. The NMF dictionaries may be trained using voice samples and noise samples. The NMF dictionaries may be applied to noisy speech data to produce an NMF representation of the speech data which may then be applied using a dynamic mask to the noisy speech data in order to suppress the noise components of the noisy speech data and produce speech enhanced data.
Type:
Grant
Filed:
October 19, 2020
Date of Patent:
April 11, 2023
Assignee:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Inventors:
Mi Zhang, Kai Cao, Xiao Zeng, Haochen Sun
Abstract: Provides herein are novel compounds, compositions, and methods useful for inhibiting bacteria, such as Mycobacterium tuberculosis. These compositions and methods find many uses in medicine and research, e.g., treating subjects afflicted with active or latent bacterial infections.
Type:
Grant
Filed:
December 21, 2018
Date of Patent:
April 4, 2023
Assignee:
Board of Trustees of Michigan State University
Abstract: A dielectric coated plasmonic photoemitter is provided. An aspect of the present photonic apparatus includes a conductive photoemitter including a dielectric material coating or layered on a metallic core. The dielectric material being configured to enhance a local optical field strength and current density of the photoemitter as compared to a bare photoemitter without the dielectric layer. The dielectric layered photoemitter being tunable to transmit photoemissions from corners thereof with different photonic characteristics depending on a laser wavelength pulse received.
Type:
Application
Filed:
May 20, 2022
Publication date:
March 30, 2023
Applicant:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Inventors:
Peng ZHANG, Lin WU, Xiao XIONG, Yang ZHOU
Abstract: A passive authentication method includes, in response to receiving a requested action from a first user, obtaining a set of sensor data and categorizing first sensor data of the set of sensor data into a first modality of a set of modalities. The method includes, for the first modality of the set of modalities, determining a distance value by applying a first modality model to the first sensor data and comparing the distance value to a first verified value of the first user for the first modality. The method includes, based on the comparison, determining a first authentication decision of the distance value. The method includes, in response to the first authentication decision indicating the first sensor data corresponds to the first user, performing the requested action.
Type:
Grant
Filed:
November 27, 2019
Date of Patent:
March 21, 2023
Assignees:
Board of Trustees of Michigan State University, Ford Global Technologies LLC
Inventors:
Arun Ross, Anil K. Jain, Debayan Deb, Kwaku O. Prakah-Asante, Krishnaswamy Venkatesh Prasad
Abstract: A laser activated luminescence system is provided. Another aspect pertains to a system employing a plasma assisted vapor deposition reactor which creates diamond layers on a substrate, in combination with a laser system to at least photoactivate and anneal the diamond layers. Yet another aspect of the present system uses a laser to assist with placement of color centers, such as nitrogen vacancy centers, in diamond. The present method uses lasers to manufacture more than two activated nitrogen vacancy center nodes in a diamond substrate, with nanometer spatial resolution and at a predetermined depth.
Type:
Application
Filed:
October 26, 2022
Publication date:
March 2, 2023
Applicant:
Board of Trustees of Michigan State University
Abstract: Provided herein are vaccine composition comprising an antigen conjugated to a capsid, wherein the capsid comprises wild type or native sequence. Provided herein are also vaccine composition comprising an antigen conjugated to a capsid, wherein said capsid comprises at least one mutation, such as a non-natural mutation. Such compositions are useful in the treatment and prevention of pathogenic infections, inflammatory diseases, and neurodegenerative disease, and cancer, among others.
Type:
Grant
Filed:
April 23, 2018
Date of Patent:
February 14, 2023
Assignee:
Board of Trustees of Michigan State University
Abstract: A transparent luminescent solar concentrator (TLSC) is provided. The TLSC includes a luminophore and a waveguide that guides light emitted from the luminophore. The TLSC has a light utilization efficiency (LUE) of greater than or equal to about 1.
Type:
Application
Filed:
July 18, 2022
Publication date:
February 2, 2023
Applicant:
Board of Trustees of Michigan State University
Inventors:
Richard R. LUNT, III, Chenchen YANG, Babak BORHAN, Mehdi MOEMENI, Matthew BATES