Patents Assigned to Board of Trustees of Michigan University
  • Combination serotonin specific reuptake inhibitor and serotonin 1A receptor partial agonist for reducing L-DOPA-induced dyskinesia
    Patent number: 12285426
    Abstract: A method of treating and attenuating L-DOPA-induced dyskinesia, comprising administering an effective dose of at least one pharmacological agent, e.g., vilazodone, having serotonin-specific reuptake inhibition (SSRI) and serotonin receptor 1A (5-HT1AR) partial agonism activity, in conjunction with L-DOPA. Other agents, such as an L-DOPA decarboxylase inhibitor, e.g., carbidopa, or other adjunct treatments may also be provided.
    Type: Grant
    Filed: April 26, 2021
    Date of Patent: April 29, 2025
    Assignees: The Research Foundation for The State University of New York, Rosalind Franklin University of Medicine and Science, Board of Trustees of Michigan State University
    Inventors: Christopher Roy Bishop, Anthony West, Fredric Manfredsson
  • Process for the treatment of lignocellulosic biomass
    Publication number: 20080008783
    Abstract: A process for the treatment of biomass to render structural carbohydrates more accessible and/or digestible using concentrated ammonium hydroxide with or without anhydrous ammonia addition, is described. The process preferably uses steam to strip ammonia from the biomass for recycling. The process yields of monosaccharides from the structural carbohydrates are good, particularly as measured by the enzymatic hydrolysis of the structural carbohydrates. The monosaccharides are used as animal feeds and energy sources for ethanol production.
    Type: Application
    Filed: September 17, 2007
    Publication date: January 10, 2008
    Applicant: Board of Trustees of Michigan University
    Inventor: Bruce Dale
  • Hybrid mixed ion clay structures for polymer nanocomposite formation
    Patent number: 6414069
    Abstract: Hybrid layered silicates with galleries between the layers containing both inorganic and organic ions with different compositions in different galleries are described. The resulting hybrid layered silicates provide economical starting materials for polymers and the like.
    Type: Grant
    Filed: March 3, 2000
    Date of Patent: July 2, 2002
    Assignee: Board of Trustees of Michigan University
    Inventors: Thomas J. Pinnavaia, Zhen Wang