Abstract: A non-contact metrology system utilizes a display that can be programmed with a plurality of targets. The display targets shine on a specular surface and the reflected targets are detected by an imaging device. Based on the display pattern and the expected location of the reflected pattern, it is possible to characterize the reflective surface. The displayed pattern can be a regular array of targets and the reflected pattern detected by the imaging device is an irregular display of targets whose locations are based on the particular display pattern, the location of the display system and imaging device and the nature of the surface. Deviations of the actual location of targets from the expected location of targets is indicative of unexpected variations in the surface. Alternatively, the display has an irregular pattern of targets such that the reflected signals result in a regularly spaced array detected by the imaging device.
Type:
Application
Filed:
January 18, 2012
Publication date:
November 22, 2012
Applicant:
Arizona Board of Regents on behalf of the University of Arizona
Inventors:
Robert E. Parks, Robert A. Smythe, Peng Su, James H. Burge, Roger Angel
Abstract: This invention relates generally to trans-,trans-conjugated linoleic acid compositions and use thereof, and in particular to trans-,trans-conjugated linoleic acid produced from photoisomerization of soy oil in the presence of an antioxidant, and used in pharmaceutical, nutraceutical and human and animal food compositions for improved health. The invention also relates generally to a method for treatment and prevention of health-related disorders of obesity by administration of pharmaceutical, nutraceutical and/or food compositions containing and/or prepared from trans-,trans-conjugated linoleic acid-rich soy oil.
Type:
Application
Filed:
May 15, 2012
Publication date:
November 22, 2012
Applicant:
BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
Inventors:
Andrew Proctor, Reddy Yettella Venkata Ramesh, Latha Devareddy, Robert R. Beitle
Abstract: Model systems and methods for exploring mechanisms of carcinogenesis and the acquisition of metastatic ability, and to provide insights into potential therapeutic targets. The systems include and methods involve fusion of a stem cell and a genetically altered cell to evaluate carcinogenesis and metastasis and for the discovery and evaluation of new therapeutic targets to inhibit metastasis and other markers of carcinogenesis.
Type:
Application
Filed:
April 16, 2012
Publication date:
November 22, 2012
Applicant:
Arizona Board of Regents on behalf of the University of Arizona
Inventors:
David T. Harris, Tom C. Tsang, Xianghui He, Brian L. Pipes, Michael E. Pennington, Linda C. Meade-Tollin
Abstract: Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement including a light detector is adapted to detect light from a sample, such as a biological material. A signal corresponding to the detected light is used to characterize the sample, for example, by detecting a light-related property thereof. In one implementation, the assaying arrangement includes integrated circuitry having a light detector and a programmable processor, with the light detector generating a signal corresponding to the light and sending the signal to the processor. The processor provides an output corresponding to the signal and indicative of a characteristic of the sample.
Type:
Grant
Filed:
November 26, 2008
Date of Patent:
November 20, 2012
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Abbas El Gamal, Helmy Eltoukhy, Khaled Salama
Abstract: The current invention provide a microfluidic valve having a housing that includes a microfluid control port disposed adjacent to a microfluid exhaust port, where a movable rigid material having a first diameter is disposed in the housing between the microfluid control port and the microfluid exhaust port. The housing further includes a microfluid pressure port having a first microfluid pressure. The microfluid pressure port is connected to the microfluid exhaust port by a microfluid valve orifice having a second diameter, where the first diameter is larger than the second diameter, and when a second microfluid pressure is applied to the control port the moveable rigid material closes the microfluid valve orifice, where the first microfluid pressure is greater than the second microfluid pressure.
Type:
Grant
Filed:
March 3, 2010
Date of Patent:
November 20, 2012
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Jessica E. Melin, Donald C. Stark, James A. Weaver
Abstract: Methods and apparatus for direct detection of chemical reactions are provided. In a preferred embodiment, electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The target molecule is preferably DNA. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal.
Type:
Grant
Filed:
June 28, 2011
Date of Patent:
November 20, 2012
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Nader Pourmand, Miloslav Karhanek, Ronald W. Davis
Abstract: An electric can opener for opening a top of a metal can which includes a housing that has a top end and a front side. A can cutting mechanism is on the front side of the housing proximate the top end of the housing. A hand held jar grip is removably mounted on the top end of the housing. The housing includes an opening that at least partially receives an opener tool.
Abstract: The present invention provides a method of reconstructing a tomographic image. In a first step, a tomographic image is forward-projected along a list of geometrical lines in a GPU. This list of geometrical lines may be list-mode event data acquired from a tomographic scanner. Alternatively, the list may be a list of weighted lines derived from a sinogram, a histogram, or a timogram acquired from a tomographic scanner. Next, the list of geometrical lines is back-projected into a 3-dimensional volume using the GPU. The results of the forward- and back-projection are then used to reconstruct the tomographic image, which is then provided as an output, e.g. to make the image available for further processing. Examples of output include storage on a storage medium and display on a display device.
Type:
Grant
Filed:
February 23, 2007
Date of Patent:
November 20, 2012
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Guillem Pratx, Peter D. Olcott, Craig S. Levin
Abstract: The present invention encompasses methods and compositions for treating a bone condition. The isolated adipose tissue-derived stromal cell of the invention and products related thereto have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications such as in spinal fusion procedures.
Type:
Grant
Filed:
June 1, 2010
Date of Patent:
November 20, 2012
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Abstract: In a geo-security system, a device receives RF signals from multiple distinct classes of RF communication systems and extracts location-dependent signal parameters. A current geotag is computed from the parameters by fuzzy extractors involving quantization of the parameters and Reed-Solomon decoding to provide a reproducible unique geotag. The current geotag is compared with a stored geotag, and a geo-secured function of the device is executed based on the result of the comparison. The use of multiple signal sources of different types, combined with special fuzzy extractors provides a robust geotag that allows both lower false rejection rate and lower false acceptance rate.
Type:
Grant
Filed:
January 25, 2010
Date of Patent:
November 20, 2012
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Di Qiu, Sherman Lo, David S. De Lorenzo, Dan Boneh, Per Enge
Abstract: The present invention provides for compositions comprising carbon nanotubes (CNT) and gold (Au). The present invention further provides methods of manufacture of gold-carbon nanotubes (gCNT). The present invention provides methods of using gCNT for biological application.
Type:
Grant
Filed:
June 13, 2008
Date of Patent:
November 20, 2012
Assignee:
Board of Trustees of the University of Arkansas
Inventors:
Jin-Woo Kim, Russell Deaton, Vladimir P. Zharov
Abstract: Methods and apparatuses for detecting faults and optimizing phase currents in an electromechanical energy converter are disclosed. An example method comprises: measuring a current of a phase of the electromechanical energy converter, modeling the electromechanical energy converter with the current measurement input into a field reconstruction module, calculating a flux linkage of the electromechanical energy converter, comparing the flux linkage with a flux linkage from a no fault electromechanical energy converter, and optimizing the current of the phase of the electromechanical energy converter in response to the comparison. Other embodiments are described and claimed.
Type:
Grant
Filed:
July 17, 2010
Date of Patent:
November 20, 2012
Assignee:
Board of Regents, The University of Texas System
Abstract: A linker system is provided where a small molecule reactive group, e.g., an activity based probe which binds to certain enzymes at the active site, is linked through an aryl diazo linker to an affinity molecule such as biotin. The reactive group may comprise a number of functionalities known to react with a specific target to be studied. This enables the probe to be exposed to analytes, such as proteins and bind specifically to them to form a complex having an affinity molecule allowing immobilization of the bound analyte on an affinity column or other support, e.g. with streptavidin. Then, the linker is cleaved without causing removal of the affinity group or dissociation of the probe from the analyte. The linker is cleaved under mild reducing conditions, e.g., dithionite. The probe is synthesized along with the linker on a solid support.
Type:
Grant
Filed:
August 1, 2007
Date of Patent:
November 20, 2012
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Matthew S. Bogyo, Steven H. L. Verhelst, Marko Fonovic
Abstract: The present application pertains generally to medical systems and methods for creation of an autologous tissue valves within a mammalian body. In some embodiments, a system for creating an endoluminal valve from a blood vessel wall is provided. The system includes a tubular assembly having a longitudinal axis, a proximal end, a distal portion with a distal end, and a first lumen extending from the proximal end to a distal port located proximate the distal portion. The distal portion can have a supporting surface that extends in a longitudinal direction and is offset from a surface of the tubular assembly proximal the distal port. The system can further include a tissue dissection probe disposed within the first lumen.
Type:
Application
Filed:
April 18, 2012
Publication date:
November 15, 2012
Applicant:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Fletcher T. Wilson, Rhunjay J. Yu, Ben Cline
Abstract: A portable active fluid-powered ankle foot orthosis. A lower leg mount and a foot bed are pivotally coupled at or proximate to an ankle position. A fluid powered rotary actuator is configured to receive power from a wearable fluid power source and provide controlled force and resistance to aid or inhibit relative rotation of the foot bed and the lower leg mount. An integral controller is provided for receiving data from sensors and controlling the fluid powered rotary actuator to actively assist gait of a user.
Type:
Application
Filed:
March 14, 2012
Publication date:
November 15, 2012
Applicant:
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
Inventors:
Elizabeth T. Hsiao-Wecksler, K. Alex Shorter, Vito Gervasi, Douglas L. Cook, Richard Remmers, Geza F. Kogler, William K. Durfee
Abstract: A method of modulating or controlling connexin 43 (Cx43) level of a cell includes inducing mitochondrial reactive oxygen species (ROS) production in the cell.
Type:
Application
Filed:
June 21, 2012
Publication date:
November 15, 2012
Applicants:
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, U.S. DEPARTMENT OF VETERANS AFFAIRS
Abstract: A spintronic device and a method for making said spintronic device. The spintronic device includes an epitaxial crystalline ferromagnetic oxide formed directly on the semiconductor material thereby allowing spin-polarized current to be efficiently injected from the ferromagnetic oxide into the semiconductor material. A host crystal lattice includes multiple sets of stacked oxide layers of material A and B of a perovskite structure with a formula of ABO3. After an oxide layer of B is grown, magnetic ions are introduced to intermix with the B material, which may replace some of the ions of the B material. The process of growing additional stacked oxide layers of material A and B and introducing further magnetic ions after the deposition of the oxide layer of B continues until enough magnetic ions are sufficiently close to one another that they align in the same direction thereby forming a ferromagnetic oxide on the semiconductor material.
Type:
Application
Filed:
May 7, 2012
Publication date:
November 15, 2012
Applicant:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Inventors:
Alexander A. Demkov, Agham-Bayan S. Posadas
Abstract: A practical and environmentally-friendly method, i.e. the high temperature-mechanical mixing by using an internal mixing device and a two-roll open milling device is used to produce the carbon blacks-free electrically conductive sulfur-vulcanised rubber blends of solid poly(butadiene-co-acrylonitrile) and solid sulfonic acid doped polyaniline. The addition of sulfur vulcanisation system does not affect the electrical properties of the vulcanised blends. All vulcanised blends prepared by using this method show useful electrical conductivities up to the order of 10?2 S/cm, good tensile strengths up to 18.0 MPa and colourable with the addition of a whitening agent. As a result, they have good potential to be used for manufacturing any antistatic products, electrostatic discharge or dissipative products and electromagnetic or radio frequency interferences shielding products.
Abstract: A new OCT system and method are disclosed, where the system includes a probe equipped with a heating element and a high heat conductive member to warm a tissue site to be scanned to an elevated and/or to maintain the elevated tissue temperature with a temperature variation of less than or equal to 1° C. to improve an accuracy and reliability of an OCT glucose concentration value other long measurement durations. The new OCT system and method can also be equipped with pressure components to reduce a pressure exerted on the tissue site to a minimal constant pressure.
Type:
Application
Filed:
June 29, 2012
Publication date:
November 15, 2012
Applicant:
The Board of Regents of the University of Texas System