Abstract: Topical formulations comprising soft glycopyrrolates are useful for treating excessive sweating conditions in subjects, such as humans suffering from hyperhidrosis. Preferably, at least one soft anticholinergic agent is provided in an effective amount or concentration in an anhydrous formulation that can inhibit excessive perspiration resulting from a condition such as hyperhidrosis.
Type:
Grant
Filed:
November 30, 2020
Date of Patent:
July 6, 2021
Assignee:
Bodor Laboratories, Inc.
Inventors:
Nicholas S. Bodor, John J. Koleng, David Angulo
Abstract: Topical formulations comprising soft glycopyrrolates are useful for treating excessive sweating conditions in subjects, such as humans suffering from hyperhidrosis. Preferably, at least one soft anticholinergic agent is provided in an effective amount or concentration in an anhydrous formulation that can inhibit excessive perspiration resulting from a condition such as hyperhidrosis.
Type:
Application
Filed:
March 12, 2015
Publication date:
January 26, 2017
Applicant:
Bodor Laboratories, Inc.
Inventors:
NICHOLAS S. BODOR, JOHN J. KOLENG, DAVID ANGULO
Abstract: Soft anticholinergic esters of the formulas: wherein R1 and R2 are both phenyl or one of R1 and R2 is phenyl and the other is cyclopentyl; R is C1-C8 alkyl, straight or branched chain; and X? is an anion with a single negative charge; and wherein each asterisk marks a chiral center; said compound having the R, S or RS stereoisomeric configuration at each chiral center unless specified otherwise, or being a mixture thereof.