Abstract: This invention relates to topical compositions for combating ectoparasites and endoparasites in animals, comprising at least one isoxazoline active agent and a pharmaceutically acceptable carrier, optionally in combination with one or more additional active agents. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the compositions of the invention to the animal in need thereof.
Type:
Grant
Filed:
October 5, 2016
Date of Patent:
August 20, 2019
Assignee:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Inventors:
Mark D. Soll, Joseph K. Rosentel, Jr., Monica Tejwani-Motwani, Carol Belansky
Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
Type:
Application
Filed:
April 24, 2019
Publication date:
August 15, 2019
Applicant:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Inventors:
Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.
Type:
Application
Filed:
April 23, 2019
Publication date:
August 15, 2019
Applicant:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Inventors:
Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Q. Meng, Hyoung Ik Lee
Abstract: The present invention encompasses FMDV vaccines or compositions. The vaccine or composition may be a vaccine or composition containing FMDV antigens. The invention also encompasses recombinant vectors encoding and expressing FMDV antigens, epitopes or immunogens which can be used to protect animals, in particular ovines, bovines, caprines, or swines, against FMDV. The invention further encompasses methods of making or producing antigenic polypeptides or antigens.
Type:
Grant
Filed:
February 5, 2018
Date of Patent:
July 30, 2019
Assignee:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Abstract: The present invention provides an effective vaccine for Marek's disease, which may be prepared using a recombinant Marek's Disease Virus (MDV), strain CVI988, having been transformed with a foreign DNA construct that includes a long terminal repeat sequence of a reticuloendotheliosis virus. This safe viral agent elicits a highly protective immune response in a chicken against virulent MDV challenge without causing a significant degree of pathogenicity. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent, along with a pharmaceutically acceptable carrier or diluent.
Type:
Application
Filed:
January 30, 2019
Publication date:
July 18, 2019
Applicant:
Boehringer Ingelheim Animal Health USA Inc.
Inventors:
Joyce Pritchard, Teshome Mebatsion, Michel Bublot
Abstract: The present invention provides vectors that contain and express in vivo or in vitro one or more Hendra virus polypeptides or antigens that elicit an immune response in animal or human against Hendra virus and Nipah virus, compositions comprising said vectors and/or Hendra virus polypeptides, methods of vaccination against Hendra virus and Nipah virus, and kits for use with such methods and compositions.
Type:
Grant
Filed:
August 10, 2016
Date of Patent:
July 16, 2019
Assignee:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Abstract: The present invention encompasses engineered Newcastle Disease Virus (NDV) vaccines or compositions. The vaccine or composition may be a recombinant vaccine. The invention also encompasses recombinant vectors encoding and expressing avian pathogen antigens, more specifically avian influenza proteins, epitopes or immunogens. Such vaccines or compositions can be used to protect animals, in particular avian, against disease.
Type:
Grant
Filed:
February 16, 2017
Date of Patent:
July 16, 2019
Assignee:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Inventors:
Michel Bublot, Frederic Reynard, François-Xavier Le Gros
Abstract: A system and method are disclosed for tracking animals, which may include production animals as well as pets. The system and method may comprise a tag system that is attached to an animal that generally has at least a near-field-communication (NFC) tag. The tag system comprises at least an NFC tag and a radio-frequency identification (RFID) tag. For NFC tags, such tags may be read with a portable computing device, such as a mobile telephone running NFC reader application software. The phone may communicate with a communications network and ultimately a computer server in order to relay information received from a respective electronic tag. The electronic tags may be fastened, embedded, or ingested by an animal. The electronic tags may be part of a mechanical coupling. Each mechanical coupling may comprise a different structure depending on the whether the tags are fastened to, embedded in, or ingested by the animal.
Type:
Grant
Filed:
March 30, 2017
Date of Patent:
July 9, 2019
Assignee:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.
Type:
Grant
Filed:
December 14, 2016
Date of Patent:
July 9, 2019
Assignee:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Inventors:
Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Q. Meng, Hyoung Ik Lee
Abstract: The present invention relates to naphthyl- or isoquinolinyl-substituted isothiazoline compounds of formula I wherein the variables are as defined in the claims and description. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.
Type:
Grant
Filed:
June 23, 2014
Date of Patent:
June 25, 2019
Assignee:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Inventors:
Pascal Bindschädler, Wolfgang Von Deyn, Karsten Körber, Deborah L. Culbertson, Koshi Gunjima, Franz Josef Braun
Abstract: The present invention provides recombinant herpesvirus of turkeys (HVT) vectors that contain and express antigens of avian pathogens, compositions comprising the recombinant HVT vectors and polyvalent vaccines comprising the recombinant HVT vectors. The present invention further provides methods of vaccination against a variety of avian pathogens and method of producing the recombinant HVT vectors.
Type:
Grant
Filed:
December 13, 2017
Date of Patent:
June 18, 2019
Assignee:
BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.
Inventors:
Michel Bublot, Teshome Mebatsion, Joyce Pritchard, Perry Linz, Aemro Kassa
Abstract: Use of a compound having the formula (I) in the manufacture of a medicament for the prevention or treatment of a disease caused by oral bacteria in an animal wherein R1 is a straight or branched alkyl group containing 8 to 16 carbon atoms at the 2- or 3-position of the morpholino ring, and R2 is a straight or branched alkyl group containing 2 to 10 carbon atoms, substituted with a hydroxy group except in the alpha-position, or a pharmaceutically acceptable salt thereof.
Type:
Application
Filed:
February 15, 2019
Publication date:
June 13, 2019
Applicants:
Boehringer Ingelheim Animal Health USA Inc., MAELOR LABORATORIES LIMITED