Abstract: The present application relates to a process for preparing the CGRP-antagonist 1-[N2-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine of formula by means of which this compound can be prepared in large amounts, in high yields and with high purity.
Type:
Application
Filed:
January 20, 2005
Publication date:
September 1, 2005
Applicant:
Boehringer Ingelheim International GambH
Inventors:
Guenter Linz, Wolfgang Broeder, Georg Zerban, Eric Winter, Bernd Schmitt, Svenja Renner, Bjoern Weyell, Heinz-Peter Schmitt