Abstract: The present invention relates to a bone implant comprising a porous body comprising particles of bioactive glass having a particle size of at least 500 ?m, wherein the composition of the bioactive glass is 45-59 weight-% of SiO2, 18-25 weight-% of Na2O, 17-25 weight-% of CaO and 0.1-6 weight-% of P2O5, and a film having a thickness of 10 ?m-200 ?m, made of a biocompatible polymer and arranged at least partially around the body.
Type:
Application
Filed:
October 4, 2017
Publication date:
February 6, 2020
Applicant:
BonAlive Biomaterials Oy
Inventors:
Fredrik OLLILA, Nina LINDFORS, Robert BJORKENHEIM, Gustav STROMBERG, Leena HUPA, Peter UPPSTU, Jukka PAJARINEN
Abstract: The present invention relates to an implantable paste comprising bioactive glass powder having a size distribution of 0.5-45 ?m, bioactive glass granules having a size distribution between 100 and 4000 ?m, low molecular weight polyethylene glycol having a molecular weight range of 200-700 g/mol, medium molecular weight polyethylene glycol having a molecular weight range of 700-2500 g/mol, high molecular weight polyethylene glycol having a molecular weight range of 2500-8000 g/mol and glycerol. The composition of the bioactive glass is 45-55 weight-% of SiO2, 20-25 weight-% of Na2O, 18-25 weight-% of CaO and 3-6 weight-% of P2O5, and the molecular weight of the low molecular weight polyethylene glycol and of the medium molecular weight polyethylene glycol differ from each other by at least 80 g/mol and that the molecular weight of the medium molecular weight polyethylene glycol and of the high molecular weight polyethylene glycol differ from each other by at least 300 g/mol.
Type:
Application
Filed:
March 16, 2015
Publication date:
March 16, 2017
Applicant:
BonAlive Biomaterials Oy
Inventors:
Lorenzo DRAGO, Carlo Luca ROMANO, Jimmy LUCCHESI, Fredrik OLLILA
Abstract: The present invention relates to an implantable paste comprising bioactive glass spheres having a size distribution of 50-425 ?m, low molecular weight polyethylene glycol having a molecular weight range of 200-700 g/mol, medium molecular weight polyethylene glycol having a molecular weight range of 700-2500 g/mol and high molecular weight polyethylene glycol having a molecular weight range of 2500-8000 g/mol, with the proviso that the molecular weight of the low molecular weight polyethylene glycol and of the medium molecular weight polyethylene glycol differ from each other by at least 80 g/mol and that the molecular weight of the medium molecular weight polyethylene glycol and of the high molecular weight polyethylene glycol differ from each other by at least 300 g/mol.
Type:
Grant
Filed:
November 12, 2010
Date of Patent:
October 14, 2014
Assignee:
Bonalive Biomaterials Oy
Inventors:
Jukka Tuominen, Timo Lehtonen, Fredrik Ollila